Functional Significance of Aurora Kinases-p53 Protein Family Interactions in Cancer

Functional Significance of Aurora Kinases-p53 Protein Family Interactions in Cancer

Aurora kinases play critical roles in regulating spindle assembly, chromosome segregation and cytokinesis to ensure faithful segregation of chromosomes during mitotic cell division cycle. Molecular and cell biological studies have revealed that Aurora kinases, at physiological levels, orchestrate co...

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Bibliographic Details
Main Authors:	Kaori Sasai, Warapen Treekitkarnmongkol, Kazuharu Kai, Hiroshi Katayama, Subrata Sen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-11-01
Series:	Frontiers in Oncology
Subjects:	Chromosome instability tumorigenesis pluripotency Aurora kinases Centrosome amplification p53 tumor suppressor protein family
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fonc.2016.00247/full

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