A Comparative Study of the Lipophilicity of Metformin and Phenformin

A Comparative Study of the Lipophilicity of Metformin and Phenformin

The results presented in this paper confirm the beneficial role of an easy-to-use and low-cost thin-layer chromatography (TLC) technique for describing the retention behavior and the experimental lipophilicity parameter of two biguanide derivatives, metformin and phenformin, in both normal-phase (NP...

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Bibliographic Details
Main Authors: Małgorzata Dołowy, Josef Jampilek, Katarzyna Bober-Majnusz
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Molecules
Subjects:
metformin
phenformin
lipophilicity
topological indices
logP
Online Access:https://www.mdpi.com/1420-3049/26/21/6613

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