Surgical Management and Outcomes of Pediatric Congenital Head and Neck Teratomas: A Scoping Review
Abstract Objective To perform a scoping review to characterize postoperative outcomes of pediatric patients (ages 0‐18) with a history of congenital head and neck teratomas. Data Sources PubMed, EMBASE, Web of Science, Cochrane, Clinicaltrails.gov. Review Methods A search of multiple databases was p...
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| Format: | Article |
| Language: | English |
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Wiley
2023-07-01
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| Series: | OTO Open |
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| Online Access: | https://doi.org/10.1002/oto2.66 |
| _version_ | 1797320523616616448 |
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| author | Siddharth Patel Ansley J. Kunnath Jean‐Nicolas Gallant Ryan H. Belcher |
| author_facet | Siddharth Patel Ansley J. Kunnath Jean‐Nicolas Gallant Ryan H. Belcher |
| author_sort | Siddharth Patel |
| collection | DOAJ |
| description | Abstract Objective To perform a scoping review to characterize postoperative outcomes of pediatric patients (ages 0‐18) with a history of congenital head and neck teratomas. Data Sources PubMed, EMBASE, Web of Science, Cochrane, Clinicaltrails.gov. Review Methods A search of multiple databases was performed. Studies were included if they detailed the surgical management and outcomes of pediatric patients with a history of congenital head and neck teratomas. Results One hundred and eight studies totaling 137 patients were identified. The median gestational age at birth was 37 weeks. Respiratory distress, prompting emergent endotracheal intubation or tracheostomy, was present in most patients (58%). The ex utero intrapartum treatment (EXIT) procedure was utilized for 21 (15%) patients. The teratomas were resected after a median duration of 4 days from birth. The most common postsurgical complications were vocal cord paralysis (3%), hemorrhage (2%), and tracheomalacia (2%). Death occurred perioperatively in 2 patients (2%). Twenty‐six patients (19%) required additional surgery, and 5 patients (4%) needed adjuvant chemotherapy. Patients were monitored for a median duration of 24 months with a recurrence rate of 6%. Four recurrent cases (50%) had intracranial extension, and 88% of the recurrent cases were mature teratomas at initial histopathological diagnosis. Conclusion Most patients with congenital head and neck teratomas require emergent airway management perinatally. Excisional and surgical complications are rare, and most patients are cured of their disease with a single operation. Recurrent teratomas tend to have an intracranial extension and are likely to be of mature pathology at the time of initial diagnosis. |
| first_indexed | 2024-03-08T04:40:22Z |
| format | Article |
| id | doaj.art-e5810bb66ec84298bbf0752be5e69813 |
| institution | Directory Open Access Journal |
| issn | 2473-974X |
| language | English |
| last_indexed | 2024-03-08T04:40:22Z |
| publishDate | 2023-07-01 |
| publisher | Wiley |
| record_format | Article |
| series | OTO Open |
| spelling | doaj.art-e5810bb66ec84298bbf0752be5e698132024-02-08T13:06:11ZengWileyOTO Open2473-974X2023-07-0173n/an/a10.1002/oto2.66Surgical Management and Outcomes of Pediatric Congenital Head and Neck Teratomas: A Scoping ReviewSiddharth Patel0Ansley J. Kunnath1Jean‐Nicolas Gallant2Ryan H. Belcher3Vanderbilt University Medical Scholars Program Nashville Tennessee USASchool of Medicine Vanderbilt University Nashville Tennessee USADepartment of Otolaryngology–Head & Neck Surgery Vanderbilt University Medical Center Nashville Tennessee USADepartment of Otolaryngology–Head & Neck Surgery Vanderbilt University Medical Center Nashville Tennessee USAAbstract Objective To perform a scoping review to characterize postoperative outcomes of pediatric patients (ages 0‐18) with a history of congenital head and neck teratomas. Data Sources PubMed, EMBASE, Web of Science, Cochrane, Clinicaltrails.gov. Review Methods A search of multiple databases was performed. Studies were included if they detailed the surgical management and outcomes of pediatric patients with a history of congenital head and neck teratomas. Results One hundred and eight studies totaling 137 patients were identified. The median gestational age at birth was 37 weeks. Respiratory distress, prompting emergent endotracheal intubation or tracheostomy, was present in most patients (58%). The ex utero intrapartum treatment (EXIT) procedure was utilized for 21 (15%) patients. The teratomas were resected after a median duration of 4 days from birth. The most common postsurgical complications were vocal cord paralysis (3%), hemorrhage (2%), and tracheomalacia (2%). Death occurred perioperatively in 2 patients (2%). Twenty‐six patients (19%) required additional surgery, and 5 patients (4%) needed adjuvant chemotherapy. Patients were monitored for a median duration of 24 months with a recurrence rate of 6%. Four recurrent cases (50%) had intracranial extension, and 88% of the recurrent cases were mature teratomas at initial histopathological diagnosis. Conclusion Most patients with congenital head and neck teratomas require emergent airway management perinatally. Excisional and surgical complications are rare, and most patients are cured of their disease with a single operation. Recurrent teratomas tend to have an intracranial extension and are likely to be of mature pathology at the time of initial diagnosis.https://doi.org/10.1002/oto2.66congenital teratomacervical teratomahead and neck |
| spellingShingle | Siddharth Patel Ansley J. Kunnath Jean‐Nicolas Gallant Ryan H. Belcher Surgical Management and Outcomes of Pediatric Congenital Head and Neck Teratomas: A Scoping Review OTO Open congenital teratoma cervical teratoma head and neck |
| title | Surgical Management and Outcomes of Pediatric Congenital Head and Neck Teratomas: A Scoping Review |
| title_full | Surgical Management and Outcomes of Pediatric Congenital Head and Neck Teratomas: A Scoping Review |
| title_fullStr | Surgical Management and Outcomes of Pediatric Congenital Head and Neck Teratomas: A Scoping Review |
| title_full_unstemmed | Surgical Management and Outcomes of Pediatric Congenital Head and Neck Teratomas: A Scoping Review |
| title_short | Surgical Management and Outcomes of Pediatric Congenital Head and Neck Teratomas: A Scoping Review |
| title_sort | surgical management and outcomes of pediatric congenital head and neck teratomas a scoping review |
| topic | congenital teratoma cervical teratoma head and neck |
| url | https://doi.org/10.1002/oto2.66 |
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