Biopolymer-Based Nanogel Approach in Drug Delivery: Basic Concept and Current Developments
Due to their increased surface area, extent of swelling and active substance-loading capacity and flexibility, nanogels made from natural and synthetic polymers have gained significant interest in scientific and industrial areas. In particular, the customized design and implementation of nontoxic, b...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-06-01
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| Series: | Pharmaceutics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4923/15/6/1644 |
| _version_ | 1797593081355173888 |
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| author | Ebru Altuntaş Burcu Özkan Sevgi Güngör Yıldız Özsoy |
| author_facet | Ebru Altuntaş Burcu Özkan Sevgi Güngör Yıldız Özsoy |
| author_sort | Ebru Altuntaş |
| collection | DOAJ |
| description | Due to their increased surface area, extent of swelling and active substance-loading capacity and flexibility, nanogels made from natural and synthetic polymers have gained significant interest in scientific and industrial areas. In particular, the customized design and implementation of nontoxic, biocompatible, and biodegradable micro/nano carriers makes their usage very feasible for a range of biomedical applications, including drug delivery, tissue engineering, and bioimaging. The design and application methodologies of nanogels are outlined in this review. Additionally, the most recent advancements in nanogel biomedical applications are discussed, with particular emphasis on applications for the delivery of drugs and biomolecules. |
| first_indexed | 2024-03-11T02:03:43Z |
| format | Article |
| id | doaj.art-e58158c8ecc04556976b1e54265810d6 |
| institution | Directory Open Access Journal |
| issn | 1999-4923 |
| language | English |
| last_indexed | 2024-03-11T02:03:43Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj.art-e58158c8ecc04556976b1e54265810d62023-11-18T12:04:25ZengMDPI AGPharmaceutics1999-49232023-06-01156164410.3390/pharmaceutics15061644Biopolymer-Based Nanogel Approach in Drug Delivery: Basic Concept and Current DevelopmentsEbru Altuntaş0Burcu Özkan1Sevgi Güngör2Yıldız Özsoy3Faculty of Pharmacy, Department of Pharmaceutical Technology, Istanbul University, 34116 Istanbul, TürkiyeGraduate School of Natural and Applied Science, Yildiz Technical University, 34220 Istanbul, TürkiyeFaculty of Pharmacy, Department of Pharmaceutical Technology, Istanbul University, 34116 Istanbul, TürkiyeFaculty of Pharmacy, Department of Pharmaceutical Technology, Istanbul University, 34116 Istanbul, TürkiyeDue to their increased surface area, extent of swelling and active substance-loading capacity and flexibility, nanogels made from natural and synthetic polymers have gained significant interest in scientific and industrial areas. In particular, the customized design and implementation of nontoxic, biocompatible, and biodegradable micro/nano carriers makes their usage very feasible for a range of biomedical applications, including drug delivery, tissue engineering, and bioimaging. The design and application methodologies of nanogels are outlined in this review. Additionally, the most recent advancements in nanogel biomedical applications are discussed, with particular emphasis on applications for the delivery of drugs and biomolecules.https://www.mdpi.com/1999-4923/15/6/1644biopolymersnanogelsdrug deliverypolysaccharide-based nanogelsprotein-based nanogelsnanotechnology |
| spellingShingle | Ebru Altuntaş Burcu Özkan Sevgi Güngör Yıldız Özsoy Biopolymer-Based Nanogel Approach in Drug Delivery: Basic Concept and Current Developments Pharmaceutics biopolymers nanogels drug delivery polysaccharide-based nanogels protein-based nanogels nanotechnology |
| title | Biopolymer-Based Nanogel Approach in Drug Delivery: Basic Concept and Current Developments |
| title_full | Biopolymer-Based Nanogel Approach in Drug Delivery: Basic Concept and Current Developments |
| title_fullStr | Biopolymer-Based Nanogel Approach in Drug Delivery: Basic Concept and Current Developments |
| title_full_unstemmed | Biopolymer-Based Nanogel Approach in Drug Delivery: Basic Concept and Current Developments |
| title_short | Biopolymer-Based Nanogel Approach in Drug Delivery: Basic Concept and Current Developments |
| title_sort | biopolymer based nanogel approach in drug delivery basic concept and current developments |
| topic | biopolymers nanogels drug delivery polysaccharide-based nanogels protein-based nanogels nanotechnology |
| url | https://www.mdpi.com/1999-4923/15/6/1644 |
| work_keys_str_mv | AT ebrualtuntas biopolymerbasednanogelapproachindrugdeliverybasicconceptandcurrentdevelopments AT burcuozkan biopolymerbasednanogelapproachindrugdeliverybasicconceptandcurrentdevelopments AT sevgigungor biopolymerbasednanogelapproachindrugdeliverybasicconceptandcurrentdevelopments AT yıldızozsoy biopolymerbasednanogelapproachindrugdeliverybasicconceptandcurrentdevelopments |