Do obese patients benefit from isolated aortic valve replacement through a partial upper sternotomy?

Abstract Objective Controversial opinions exist for aortic valve replacement (AVR) through partial upper sternotomy in obese patients. Moreover, this study sought to investigate the potential clinical advantage of partial upper sternotomy aortic valve replacement (mini-AVR) over conventional full st...

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Main Authors: Xian-Biao Xie, Xiao-Fu Dai, Zhi-Huang Qiu, De-Bin Jiang, Qing-Song Wu, Yi Dong, Liang-Wan Chen
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Journal of Cardiothoracic Surgery
Subjects:
Online Access:https://doi.org/10.1186/s13019-022-01926-3
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author Xian-Biao Xie
Xiao-Fu Dai
Zhi-Huang Qiu
De-Bin Jiang
Qing-Song Wu
Yi Dong
Liang-Wan Chen
author_facet Xian-Biao Xie
Xiao-Fu Dai
Zhi-Huang Qiu
De-Bin Jiang
Qing-Song Wu
Yi Dong
Liang-Wan Chen
author_sort Xian-Biao Xie
collection DOAJ
description Abstract Objective Controversial opinions exist for aortic valve replacement (AVR) through partial upper sternotomy in obese patients. Moreover, this study sought to investigate the potential clinical advantage of partial upper sternotomy aortic valve replacement (mini-AVR) over conventional full sternotomy aortic valve replacement (con-AVR) in obese patients. Methods This was a retrospective and observational study. From January 2015 to December 2020, a total of 184 obese [body mass index (BMI) ≥ 30 kg  m2] patients undergoing isolated primary AVR were included: 98 patients underwent conventional full sternotomy, and 86 patients underwent partial upper sternotomy. Propensity score (PS) matching was applied to eliminate the bassline imbalances in the mini-AVR and the con-AVR groups. Results After one-to-one propensity score matching, two groups of 60 patients were obtained. No in-hospital death occurred in the two groups. In addition, cardiopulmonary bypass time and total operative time were similar across the 2 groups, but the aortic cross-clamp time was significantly shorter in the con-AVR group (P = .0.022). The amount of mediastinal drainage at 48 h after surgery (P =  0.018) and postoperative blood transfusions (P =  0.014) were significantly lower in the mini-AVR group. There was no difference in ventilation time (P = .0.145), but a shorter intensive care unit stay time (P =  0.021) in the mini-AVR group. Conclusion This study demonstrates that aortic valve replacement through a mini-AVR in obese patients is a safe and effective procedure. It outperformed con-AVR in terms of blood loss, blood product transfusion, and ICU stay.
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spelling doaj.art-e5816f9bd2954b1fb0508f6b028a9b0b2022-12-22T01:32:26ZengBMCJournal of Cardiothoracic Surgery1749-80902022-08-011711610.1186/s13019-022-01926-3Do obese patients benefit from isolated aortic valve replacement through a partial upper sternotomy?Xian-Biao Xie0Xiao-Fu Dai1Zhi-Huang Qiu2De-Bin Jiang3Qing-Song Wu4Yi Dong5Liang-Wan Chen6Department of Cardiovascular Surgery, Union Hospital, Fujian Medical UniversityDepartment of Cardiovascular Surgery, Union Hospital, Fujian Medical UniversityDepartment of Cardiovascular Surgery, Union Hospital, Fujian Medical UniversityDepartment of Cardiovascular Surgery, Union Hospital, Fujian Medical UniversityDepartment of Cardiovascular Surgery, Union Hospital, Fujian Medical UniversityDepartment of Cardiovascular Surgery, Union Hospital, Fujian Medical UniversityDepartment of Cardiovascular Surgery, Union Hospital, Fujian Medical UniversityAbstract Objective Controversial opinions exist for aortic valve replacement (AVR) through partial upper sternotomy in obese patients. Moreover, this study sought to investigate the potential clinical advantage of partial upper sternotomy aortic valve replacement (mini-AVR) over conventional full sternotomy aortic valve replacement (con-AVR) in obese patients. Methods This was a retrospective and observational study. From January 2015 to December 2020, a total of 184 obese [body mass index (BMI) ≥ 30 kg  m2] patients undergoing isolated primary AVR were included: 98 patients underwent conventional full sternotomy, and 86 patients underwent partial upper sternotomy. Propensity score (PS) matching was applied to eliminate the bassline imbalances in the mini-AVR and the con-AVR groups. Results After one-to-one propensity score matching, two groups of 60 patients were obtained. No in-hospital death occurred in the two groups. In addition, cardiopulmonary bypass time and total operative time were similar across the 2 groups, but the aortic cross-clamp time was significantly shorter in the con-AVR group (P = .0.022). The amount of mediastinal drainage at 48 h after surgery (P =  0.018) and postoperative blood transfusions (P =  0.014) were significantly lower in the mini-AVR group. There was no difference in ventilation time (P = .0.145), but a shorter intensive care unit stay time (P =  0.021) in the mini-AVR group. Conclusion This study demonstrates that aortic valve replacement through a mini-AVR in obese patients is a safe and effective procedure. It outperformed con-AVR in terms of blood loss, blood product transfusion, and ICU stay.https://doi.org/10.1186/s13019-022-01926-3Aortic valve replacementObesityPartial upper sternotomy
spellingShingle Xian-Biao Xie
Xiao-Fu Dai
Zhi-Huang Qiu
De-Bin Jiang
Qing-Song Wu
Yi Dong
Liang-Wan Chen
Do obese patients benefit from isolated aortic valve replacement through a partial upper sternotomy?
Journal of Cardiothoracic Surgery
Aortic valve replacement
Obesity
Partial upper sternotomy
title Do obese patients benefit from isolated aortic valve replacement through a partial upper sternotomy?
title_full Do obese patients benefit from isolated aortic valve replacement through a partial upper sternotomy?
title_fullStr Do obese patients benefit from isolated aortic valve replacement through a partial upper sternotomy?
title_full_unstemmed Do obese patients benefit from isolated aortic valve replacement through a partial upper sternotomy?
title_short Do obese patients benefit from isolated aortic valve replacement through a partial upper sternotomy?
title_sort do obese patients benefit from isolated aortic valve replacement through a partial upper sternotomy
topic Aortic valve replacement
Obesity
Partial upper sternotomy
url https://doi.org/10.1186/s13019-022-01926-3
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