Dendritic cells based immunotherapy of patient with chondrosarcoma--case report.
We present a case report of patient with intracranial chondrosarcoma and attempt to use vaccination of dendritic cells as the salvage therapy. To our knowledge, this is the first case report of DCs vaccination in the head and neck chondrosarcoma. Immunotherapy with allogeneic DCs stimulated with tum...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Via Medica
2008-06-01
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| Series: | Folia Histochemica et Cytobiologica |
| Online Access: | http://czasopisma.viamedica.pl/fhc/article/view/4437 |
| _version_ | 1828764117464252416 |
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| author | Anna Dmoszyńska Adam Kłos Beata Piechnik Krzysztof Giannopoulos Paulina Wdowiak Magdalena Wasiak Iwona Hus Sebastian Radej Jacek Tabarkiewicz Jacek Rolinski |
| author_facet | Anna Dmoszyńska Adam Kłos Beata Piechnik Krzysztof Giannopoulos Paulina Wdowiak Magdalena Wasiak Iwona Hus Sebastian Radej Jacek Tabarkiewicz Jacek Rolinski |
| author_sort | Anna Dmoszyńska |
| collection | DOAJ |
| description | We present a case report of patient with intracranial chondrosarcoma and attempt to use vaccination of dendritic cells as the salvage therapy. To our knowledge, this is the first case report of DCs vaccination in the head and neck chondrosarcoma. Immunotherapy with allogeneic DCs stimulated with tumor cell lysates in this case was demonstrated to be feasible, safe and well tolerated. Unfortunately we did not observe any clinical or immune response during vaccination. CD4+ and CD8+ regulatory cells could be responsible for ineffectiveness of immunotherapy. |
| first_indexed | 2024-12-11T02:14:58Z |
| format | Article |
| id | doaj.art-e58589bb696241899285aa2d511e8938 |
| institution | Directory Open Access Journal |
| issn | 0239-8508 1897-5631 |
| language | English |
| last_indexed | 2024-12-11T02:14:58Z |
| publishDate | 2008-06-01 |
| publisher | Via Medica |
| record_format | Article |
| series | Folia Histochemica et Cytobiologica |
| spelling | doaj.art-e58589bb696241899285aa2d511e89382022-12-22T01:24:12ZengVia MedicaFolia Histochemica et Cytobiologica0239-85081897-56312008-06-0146216517010.5603/4437Dendritic cells based immunotherapy of patient with chondrosarcoma--case report.Anna DmoszyńskaAdam KłosBeata PiechnikKrzysztof GiannopoulosPaulina WdowiakMagdalena WasiakIwona HusSebastian RadejJacek TabarkiewiczJacek RolinskiWe present a case report of patient with intracranial chondrosarcoma and attempt to use vaccination of dendritic cells as the salvage therapy. To our knowledge, this is the first case report of DCs vaccination in the head and neck chondrosarcoma. Immunotherapy with allogeneic DCs stimulated with tumor cell lysates in this case was demonstrated to be feasible, safe and well tolerated. Unfortunately we did not observe any clinical or immune response during vaccination. CD4+ and CD8+ regulatory cells could be responsible for ineffectiveness of immunotherapy.http://czasopisma.viamedica.pl/fhc/article/view/4437 |
| spellingShingle | Anna Dmoszyńska Adam Kłos Beata Piechnik Krzysztof Giannopoulos Paulina Wdowiak Magdalena Wasiak Iwona Hus Sebastian Radej Jacek Tabarkiewicz Jacek Rolinski Dendritic cells based immunotherapy of patient with chondrosarcoma--case report. Folia Histochemica et Cytobiologica |
| title | Dendritic cells based immunotherapy of patient with chondrosarcoma--case report. |
| title_full | Dendritic cells based immunotherapy of patient with chondrosarcoma--case report. |
| title_fullStr | Dendritic cells based immunotherapy of patient with chondrosarcoma--case report. |
| title_full_unstemmed | Dendritic cells based immunotherapy of patient with chondrosarcoma--case report. |
| title_short | Dendritic cells based immunotherapy of patient with chondrosarcoma--case report. |
| title_sort | dendritic cells based immunotherapy of patient with chondrosarcoma case report |
| url | http://czasopisma.viamedica.pl/fhc/article/view/4437 |
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