Are Truelove and Witts criteria for diagnosing acute severe colitis relevant for the Indian population? A prospective study
Background/AimsTruelove and Witts criteria have been used to define acute severe colitis since the 1950s. However, hemoglobin (an additional criterion of the definition) levels in the general population in developing countries are lower than in the population of developed countries. We aimed to dete...
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| Format: | Article |
| Language: | English |
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Korean Association for the Study of Intestinal Diseases
2018-01-01
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| Series: | Intestinal Research |
| Subjects: | |
| Online Access: | http://www.irjournal.org/upload/pdf/ir-16-69.pdf |
| _version_ | 1819242307646390272 |
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| author | Saransh Jain Saurabh Kedia Sawan Bopanna Dawesh P Yadav Sandeep Goyal Peush Sahni Sujoy Pal Nihar Ranjan Dash Govind Makharia Simon P. L. Travis Vineet Ahuja |
| author_facet | Saransh Jain Saurabh Kedia Sawan Bopanna Dawesh P Yadav Sandeep Goyal Peush Sahni Sujoy Pal Nihar Ranjan Dash Govind Makharia Simon P. L. Travis Vineet Ahuja |
| author_sort | Saransh Jain |
| collection | DOAJ |
| description | Background/AimsTruelove and Witts criteria have been used to define acute severe colitis since the 1950s. However, hemoglobin (an additional criterion of the definition) levels in the general population in developing countries are lower than in the population of developed countries. We aimed to determine the relevance of Truelove and Witts criteria in the Indian population.MethodsConsecutive patients with acute severe colitis satisfying the Truelove and Witts criteria, hospitalized at a single center between April 2015 and December 2016 were included. All patients received intravenous corticosteroids and 16 required colectomy. The hemoglobin levels at admission were subsequently excluded from the classification criteria, and the effect this had on the criteria for diagnosis was determined.ResultsOut of 61 patients of acute severe colitis diagnosed according to the original Truelove and Witts criteria, 12 patients (20%) had 1 additional criterion, 33 (54%) had 2 additional criteria and 16 (26%) had 3 or more additional criteria in addition to 6 or more blood stained stools on admission. On excluding hemoglobin as an additional criterion from the Truelove and Witts definition, all patients still met the criteria for acute severe colitis.ConclusionsTruelove and Witts criteria can be used to define acute severe colitis in India, despite lower mean hemoglobin in the native population. |
| first_indexed | 2024-12-23T14:37:44Z |
| format | Article |
| id | doaj.art-e5885b8d62694c7da8677546e7c5d063 |
| institution | Directory Open Access Journal |
| issn | 1598-9100 2288-1956 |
| language | English |
| last_indexed | 2024-12-23T14:37:44Z |
| publishDate | 2018-01-01 |
| publisher | Korean Association for the Study of Intestinal Diseases |
| record_format | Article |
| series | Intestinal Research |
| spelling | doaj.art-e5885b8d62694c7da8677546e7c5d0632022-12-21T17:43:19ZengKorean Association for the Study of Intestinal DiseasesIntestinal Research1598-91002288-19562018-01-01161697410.5217/ir.2018.16.1.69329Are Truelove and Witts criteria for diagnosing acute severe colitis relevant for the Indian population? A prospective studySaransh Jain0Saurabh Kedia1Sawan Bopanna2Dawesh P Yadav3Sandeep Goyal4Peush Sahni5Sujoy Pal6Nihar Ranjan Dash7Govind Makharia8Simon P. L. Travis9Vineet Ahuja10Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.Department of Gastrointestinal Surgery, All India Institute of Medical Sciences, New Delhi, India.Department of Gastrointestinal Surgery, All India Institute of Medical Sciences, New Delhi, India.Department of Gastrointestinal Surgery, All India Institute of Medical Sciences, New Delhi, India.Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.Translational Gastroenterology Unit, Oxford University Hospitals, Oxford, UK.Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.Background/AimsTruelove and Witts criteria have been used to define acute severe colitis since the 1950s. However, hemoglobin (an additional criterion of the definition) levels in the general population in developing countries are lower than in the population of developed countries. We aimed to determine the relevance of Truelove and Witts criteria in the Indian population.MethodsConsecutive patients with acute severe colitis satisfying the Truelove and Witts criteria, hospitalized at a single center between April 2015 and December 2016 were included. All patients received intravenous corticosteroids and 16 required colectomy. The hemoglobin levels at admission were subsequently excluded from the classification criteria, and the effect this had on the criteria for diagnosis was determined.ResultsOut of 61 patients of acute severe colitis diagnosed according to the original Truelove and Witts criteria, 12 patients (20%) had 1 additional criterion, 33 (54%) had 2 additional criteria and 16 (26%) had 3 or more additional criteria in addition to 6 or more blood stained stools on admission. On excluding hemoglobin as an additional criterion from the Truelove and Witts definition, all patients still met the criteria for acute severe colitis.ConclusionsTruelove and Witts criteria can be used to define acute severe colitis in India, despite lower mean hemoglobin in the native population.http://www.irjournal.org/upload/pdf/ir-16-69.pdfAcute severe colitisDefinitionAnemiaTruelove and Witts criteriaIndia |
| spellingShingle | Saransh Jain Saurabh Kedia Sawan Bopanna Dawesh P Yadav Sandeep Goyal Peush Sahni Sujoy Pal Nihar Ranjan Dash Govind Makharia Simon P. L. Travis Vineet Ahuja Are Truelove and Witts criteria for diagnosing acute severe colitis relevant for the Indian population? A prospective study Intestinal Research Acute severe colitis Definition Anemia Truelove and Witts criteria India |
| title | Are Truelove and Witts criteria for diagnosing acute severe colitis relevant for the Indian population? A prospective study |
| title_full | Are Truelove and Witts criteria for diagnosing acute severe colitis relevant for the Indian population? A prospective study |
| title_fullStr | Are Truelove and Witts criteria for diagnosing acute severe colitis relevant for the Indian population? A prospective study |
| title_full_unstemmed | Are Truelove and Witts criteria for diagnosing acute severe colitis relevant for the Indian population? A prospective study |
| title_short | Are Truelove and Witts criteria for diagnosing acute severe colitis relevant for the Indian population? A prospective study |
| title_sort | are truelove and witts criteria for diagnosing acute severe colitis relevant for the indian population a prospective study |
| topic | Acute severe colitis Definition Anemia Truelove and Witts criteria India |
| url | http://www.irjournal.org/upload/pdf/ir-16-69.pdf |
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