Arab Countries and Oncology Clinical Trials: A Bibliometric Analysis
The increasing cancer burden is a major health concern in Arab countries with cross-regional variations in cancer profiles. Given the limited oncology research output and scarce data on cancer trial participation in the Arab region, this study explored the therapeutic cancer trial landscape in Arab...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-09-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/15/18/4428 |
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| author | Humaid O. Al-Shamsi Ibrahim Abu-Gheida Kareem Sameh Nouran E. Tahoun Khaled M. Musallam |
| author_facet | Humaid O. Al-Shamsi Ibrahim Abu-Gheida Kareem Sameh Nouran E. Tahoun Khaled M. Musallam |
| author_sort | Humaid O. Al-Shamsi |
| collection | DOAJ |
| description | The increasing cancer burden is a major health concern in Arab countries with cross-regional variations in cancer profiles. Given the limited oncology research output and scarce data on cancer trial participation in the Arab region, this study explored the therapeutic cancer trial landscape in Arab countries over the past 20 years. A bibliometric analysis of the PubMed database was conducted on primary publications of therapeutic trials with a participating Arab center. Arab countries participated in 320 published cancer-related therapeutic trials (2000–2021). During this period, there was a consistent increase in the number of trials, sample size, multiregional site participation, and number of randomized trials. However, most trials were small, did not receive external funding, and included a single Arab site. Compared with Arab-only trials, trials with joint non-Arab sites were larger (<i>p</i> = 0.003) and more likely to be externally funded (<i>p</i> < 0.001). Citation numbers and journal impact factors were higher in trial publications with joint non-Arab authorship than those without (<i>p</i> < 0.001, for both). Despite improving conduct and publication records of oncology trials with Arab centers, cancer trial participation remains limited in Arab countries. Concerted efforts are required to encourage sponsorship and international collaboration in this region. |
| first_indexed | 2024-03-10T22:57:45Z |
| format | Article |
| id | doaj.art-e58e9424430a476d96e97208edb21e2c |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-10T22:57:45Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-e58e9424430a476d96e97208edb21e2c2023-11-19T09:53:42ZengMDPI AGCancers2072-66942023-09-011518442810.3390/cancers15184428Arab Countries and Oncology Clinical Trials: A Bibliometric AnalysisHumaid O. Al-Shamsi0Ibrahim Abu-Gheida1Kareem Sameh2Nouran E. Tahoun3Khaled M. Musallam4Burjeel Cancer Institute, Burjeel Medical City, Abu Dhabi P.O. Box 92510, United Arab EmiratesBurjeel Cancer Institute, Burjeel Medical City, Abu Dhabi P.O. Box 92510, United Arab EmiratesPfizer Gulf FZ LLC, Dubai Media City, Dubai P.O. Box 502749, United Arab EmiratesPfizer Gulf FZ LLC, Dubai Media City, Dubai P.O. Box 502749, United Arab EmiratesBurjeel Cancer Institute, Burjeel Medical City, Abu Dhabi P.O. Box 92510, United Arab EmiratesThe increasing cancer burden is a major health concern in Arab countries with cross-regional variations in cancer profiles. Given the limited oncology research output and scarce data on cancer trial participation in the Arab region, this study explored the therapeutic cancer trial landscape in Arab countries over the past 20 years. A bibliometric analysis of the PubMed database was conducted on primary publications of therapeutic trials with a participating Arab center. Arab countries participated in 320 published cancer-related therapeutic trials (2000–2021). During this period, there was a consistent increase in the number of trials, sample size, multiregional site participation, and number of randomized trials. However, most trials were small, did not receive external funding, and included a single Arab site. Compared with Arab-only trials, trials with joint non-Arab sites were larger (<i>p</i> = 0.003) and more likely to be externally funded (<i>p</i> < 0.001). Citation numbers and journal impact factors were higher in trial publications with joint non-Arab authorship than those without (<i>p</i> < 0.001, for both). Despite improving conduct and publication records of oncology trials with Arab centers, cancer trial participation remains limited in Arab countries. Concerted efforts are required to encourage sponsorship and international collaboration in this region.https://www.mdpi.com/2072-6694/15/18/4428researchoncologyArabMiddle EastNorth Africacancer management |
| spellingShingle | Humaid O. Al-Shamsi Ibrahim Abu-Gheida Kareem Sameh Nouran E. Tahoun Khaled M. Musallam Arab Countries and Oncology Clinical Trials: A Bibliometric Analysis Cancers research oncology Arab Middle East North Africa cancer management |
| title | Arab Countries and Oncology Clinical Trials: A Bibliometric Analysis |
| title_full | Arab Countries and Oncology Clinical Trials: A Bibliometric Analysis |
| title_fullStr | Arab Countries and Oncology Clinical Trials: A Bibliometric Analysis |
| title_full_unstemmed | Arab Countries and Oncology Clinical Trials: A Bibliometric Analysis |
| title_short | Arab Countries and Oncology Clinical Trials: A Bibliometric Analysis |
| title_sort | arab countries and oncology clinical trials a bibliometric analysis |
| topic | research oncology Arab Middle East North Africa cancer management |
| url | https://www.mdpi.com/2072-6694/15/18/4428 |
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