The gut microbiota, HPA axis, and brain in adolescent-onset depression: Probiotics as a novel treatment

The gut microbiota, HPA axis, and brain in adolescent-onset depression: Probiotics as a novel treatment

Stress-associated disruptions in the development of frontolimbic regions may play a critical role in the emergence of adolescent-onset depression. These regions are particularly sensitive to Hypothalamic-Pituitary-Adrenal (HPA) axis signaling. The HPA axis is hyperactive in adolescent depression, an...

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Bibliographic Details
Main Authors: Daniel Freimer, Tony T. Yang, Tiffany C. Ho, Olga Tymofiyeva, Cherry Leung
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Adolescent
Depression
Stress
HPA axis
Neurodevelopment
Microbiota
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354622001314

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