Prolonged Alprazolam Treatment Alters Components of Glutamatergic Neurotransmission in the Hippocampus of Male Wistar Rats—The Neuroadaptive Changes following Long-Term Benzodiazepine (Mis)Use
Alprazolam (ALP), a benzodiazepine (BDZ) used to treat anxiety, panic, and sleep disorders, is one of the most prescribed psychotropic drugs worldwide. The side effects associated with long-term (mis)use of ALP have become a major challenge in pharmacotherapy, emphasizing the unmet need to further i...
Main Authors: | Marina Zaric Kontic, Milorad Dragic, Jelena Martinovic, Katarina Mihajlovic, Zeljka Brkic, Natasa Mitrovic, Ivana Grkovic |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-02-01
|
Series: | Pharmaceuticals |
Subjects: | |
Online Access: | https://www.mdpi.com/1424-8247/16/3/331 |
Similar Items
-
Alprazolam addiction: The case study
by: O. Pityk, et al.
Published: (2021-04-01) -
Effects of Alprazolam on the Follicular Development of Rat Ovaries
by: Mohammad Shadkhast, et al.
Published: (2018-05-01) -
The teratogenic effects of alprazolam intake on rat fetus
by: Takzare N, et al.
Published: (2011-01-01) -
Effects of anaerobic fermentation in a nitrogen atmosphere on bioactive compound content in Vietnamese GABA tea
by: Quoc Sinh Nguyen, et al.
Published: (2018-09-01) -
Cutaneous allergic reaction due to alprazolam in a child
by: Fevziye Toros, et al.
Published: (2016-06-01)