Plasma SARS-CoV-2 nucleocapsid antigen levels are associated with progression to severe disease in hospitalized COVID-19

Abstract Background Studies quantifying SARS-CoV-2 have focused on upper respiratory tract or plasma viral RNA with inconsistent association with clinical outcomes. The association between plasma viral antigen levels and clinical outcomes has not been previously studied. Our aim was to investigate t...

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Main Authors: Katherine D. Wick, Aleksandra Leligdowicz, Andrew Willmore, Sidney A. Carrillo, Rajani Ghale, Alejandra Jauregui, Suzanna S. Chak, Viet Nguyen, Deanna Lee, Chayse Jones, Robin Dewar, H. Clifford Lane, Kirsten N. Kangelaris, Carolyn M. Hendrickson, Kathleen D. Liu, Pratik Sinha, David J. Erle, Charles R. Langelier, Matthew F. Krummell, Prescott G. Woodruff, Carolyn S. Calfee, Michael A. Matthay, the COMET Consortium
格式: 文件
语言:English
出版: BMC 2022-09-01
丛编:Critical Care
在线阅读:https://doi.org/10.1186/s13054-022-04153-3