Gut Microbiome and Cardiovascular Diseases
Recent evidence has suggested that the gut microbiome is involved in human health and diseases, such as inflammatory bowel disease, liver cirrhosis, rheumatoid arthritis, and type 2 diabetes. Cardiovascular diseases, which are associated with high morbidity and mortality across the world, are no exc...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-06-01
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| Series: | Diseases |
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| Online Access: | http://www.mdpi.com/2079-9721/6/3/56 |
| _version_ | 1819177894230884352 |
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| author | Naofumi Yoshida Tomoya Yamashita Ken-ichi Hirata |
| author_facet | Naofumi Yoshida Tomoya Yamashita Ken-ichi Hirata |
| author_sort | Naofumi Yoshida |
| collection | DOAJ |
| description | Recent evidence has suggested that the gut microbiome is involved in human health and diseases, such as inflammatory bowel disease, liver cirrhosis, rheumatoid arthritis, and type 2 diabetes. Cardiovascular diseases, which are associated with high morbidity and mortality across the world, are no exception. Increasing evidence has suggested a strong relationship between the gut microbiome and the progression of cardiovascular diseases. We first reported such a relationship with coronary artery disease two years ago. Next-generation sequencing techniques, together with bioinformatics technology, constantly and dramatically expand our knowledge of the complex human gut bacterial ecosystem and reveal the exact role of this bacterial ecosystem in cardiovascular diseases via the functional analysis of the gut microbiome. Such knowledge may pave the way for the development of further diagnostics and therapeutics for prevention and management of cardiovascular diseases. The aim of the current review is to highlight the relationship between the gut microbiome and their metabolites, and the development of cardiovascular diseases by fostering an understanding of recent studies. |
| first_indexed | 2024-12-22T21:33:54Z |
| format | Article |
| id | doaj.art-e59b52ef94ca4b018a5086a48f3a786c |
| institution | Directory Open Access Journal |
| issn | 2079-9721 |
| language | English |
| last_indexed | 2024-12-22T21:33:54Z |
| publishDate | 2018-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diseases |
| spelling | doaj.art-e59b52ef94ca4b018a5086a48f3a786c2022-12-21T18:11:49ZengMDPI AGDiseases2079-97212018-06-01635610.3390/diseases6030056diseases6030056Gut Microbiome and Cardiovascular DiseasesNaofumi Yoshida0Tomoya Yamashita1Ken-ichi Hirata2Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe 6500017, JapanDivision of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe 6500017, JapanDivision of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe 6500017, JapanRecent evidence has suggested that the gut microbiome is involved in human health and diseases, such as inflammatory bowel disease, liver cirrhosis, rheumatoid arthritis, and type 2 diabetes. Cardiovascular diseases, which are associated with high morbidity and mortality across the world, are no exception. Increasing evidence has suggested a strong relationship between the gut microbiome and the progression of cardiovascular diseases. We first reported such a relationship with coronary artery disease two years ago. Next-generation sequencing techniques, together with bioinformatics technology, constantly and dramatically expand our knowledge of the complex human gut bacterial ecosystem and reveal the exact role of this bacterial ecosystem in cardiovascular diseases via the functional analysis of the gut microbiome. Such knowledge may pave the way for the development of further diagnostics and therapeutics for prevention and management of cardiovascular diseases. The aim of the current review is to highlight the relationship between the gut microbiome and their metabolites, and the development of cardiovascular diseases by fostering an understanding of recent studies.http://www.mdpi.com/2079-9721/6/3/56gut microbiomecardiovascular diseasesBacteroides |
| spellingShingle | Naofumi Yoshida Tomoya Yamashita Ken-ichi Hirata Gut Microbiome and Cardiovascular Diseases Diseases gut microbiome cardiovascular diseases Bacteroides |
| title | Gut Microbiome and Cardiovascular Diseases |
| title_full | Gut Microbiome and Cardiovascular Diseases |
| title_fullStr | Gut Microbiome and Cardiovascular Diseases |
| title_full_unstemmed | Gut Microbiome and Cardiovascular Diseases |
| title_short | Gut Microbiome and Cardiovascular Diseases |
| title_sort | gut microbiome and cardiovascular diseases |
| topic | gut microbiome cardiovascular diseases Bacteroides |
| url | http://www.mdpi.com/2079-9721/6/3/56 |
| work_keys_str_mv | AT naofumiyoshida gutmicrobiomeandcardiovasculardiseases AT tomoyayamashita gutmicrobiomeandcardiovasculardiseases AT kenichihirata gutmicrobiomeandcardiovasculardiseases |