Controlling Nutritional Status Score Evaluates Prognosis in Patients With Non-Muscle Invasive Bladder Cancer
Objective: We investigated the clinical value of the Controlling Nutritional Status score in evaluating the prognosis of patients with non-muscle invasive bladder cancer. Methods: We conducted a retrospective analysis of the clinical data of 88 patients with non-muscle invasive bladder cancer who un...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
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SAGE Publishing
2021-05-01
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Series: | Cancer Control |
Online Access: | https://doi.org/10.1177/10732748211021078 |
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author | Jiaguo Huang MD Liwei Zhao MD Kai Wang MD Ji Sun MD Shengcheng Tai MD Runmiao Hua MD Yufu Yu MD Yi Fan MD |
author_facet | Jiaguo Huang MD Liwei Zhao MD Kai Wang MD Ji Sun MD Shengcheng Tai MD Runmiao Hua MD Yufu Yu MD Yi Fan MD |
author_sort | Jiaguo Huang MD |
collection | DOAJ |
description | Objective: We investigated the clinical value of the Controlling Nutritional Status score in evaluating the prognosis of patients with non-muscle invasive bladder cancer. Methods: We conducted a retrospective analysis of the clinical data of 88 patients with non-muscle invasive bladder cancer who underwent transurethral resection of bladder tumor or partial cystectomy between January 2011 and May 2015 in a single center. The patients were divided into groups base on high (>1) and low (≤1) Controlling Nutritional Status score. Results: Clinical and demographic data of the patient groups were analyzed using the Kaplan-Meier method and log-rank test to generate survival curves. Univariate and multivariate analyses were conducted using the Cox proportional hazard model. Among the participants, the male-to-female ratio was 70:18 and median age was 64.5 years (range, 25-84 years). The numbers of patients with Controlling Nutritional Status score of 0, 1, 2, 3, 4, 5, and 6 were 26 (29.55%), 21 (23.86%), 20 (22.73%), 12 (13.64%), 5 (5.68%), 1 (1.14%), and 3 (3.41%), respectively. The 5-year recurrence rate was 29 out of 88 patients (32.95%). The recurrence-free survival of the high-score group was significantly lower than that of the low-score group ( P < 0.001). On univariate analysis, age, smoking history, Controlling Nutritional Status score, depth of tumor invasion, pathological grade, and tumor diameter were related to the prognosis of patients with non-muscle invasive bladder cancer. On multivariate analysis, the Controlling Nutritional Status score (hazard ratio, 4.938; 95% confidence interval, 1.392-17.525; P = 0.013) was an independent factor affecting the recurrence-free survival of patients with non-muscle-invasive bladder cancer. Conclusion: Therefore, the Controlling Nutritional Status score could be a simple, cost-effective, and reliable predictor of prognoses among of patients with non-muscle-invasive bladder cancer. |
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institution | Directory Open Access Journal |
issn | 1073-2748 |
language | English |
last_indexed | 2024-12-20T05:47:03Z |
publishDate | 2021-05-01 |
publisher | SAGE Publishing |
record_format | Article |
series | Cancer Control |
spelling | doaj.art-e59b645cc0614628be3bd519947701162022-12-21T19:51:16ZengSAGE PublishingCancer Control1073-27482021-05-012810.1177/10732748211021078Controlling Nutritional Status Score Evaluates Prognosis in Patients With Non-Muscle Invasive Bladder CancerJiaguo Huang MD0Liwei Zhao MD1Kai Wang MD2Ji Sun MD3Shengcheng Tai MD4Runmiao Hua MD5Yufu Yu MD6Yi Fan MD7 Department of Urology, Zhejiang Xiaoshan Hospital, Hangzhou, Zhejiang, China Hangzhou Normal University School of Medicine, Hangzhou, Zhejiang Province, China Department of Urology, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Zhejiang Sheng, China Department of Urology, Zhejiang Xiaoshan Hospital, Hangzhou, Zhejiang, China Department of Urology, Zhejiang Xiaoshan Hospital, Hangzhou, Zhejiang, China Department of Urology, Zhejiang Xiaoshan Hospital, Hangzhou, Zhejiang, China Department of Urology, Zhejiang Xiaoshan Hospital, Hangzhou, Zhejiang, China Department of Urology, Zhejiang Xiaoshan Hospital, Hangzhou, Zhejiang, ChinaObjective: We investigated the clinical value of the Controlling Nutritional Status score in evaluating the prognosis of patients with non-muscle invasive bladder cancer. Methods: We conducted a retrospective analysis of the clinical data of 88 patients with non-muscle invasive bladder cancer who underwent transurethral resection of bladder tumor or partial cystectomy between January 2011 and May 2015 in a single center. The patients were divided into groups base on high (>1) and low (≤1) Controlling Nutritional Status score. Results: Clinical and demographic data of the patient groups were analyzed using the Kaplan-Meier method and log-rank test to generate survival curves. Univariate and multivariate analyses were conducted using the Cox proportional hazard model. Among the participants, the male-to-female ratio was 70:18 and median age was 64.5 years (range, 25-84 years). The numbers of patients with Controlling Nutritional Status score of 0, 1, 2, 3, 4, 5, and 6 were 26 (29.55%), 21 (23.86%), 20 (22.73%), 12 (13.64%), 5 (5.68%), 1 (1.14%), and 3 (3.41%), respectively. The 5-year recurrence rate was 29 out of 88 patients (32.95%). The recurrence-free survival of the high-score group was significantly lower than that of the low-score group ( P < 0.001). On univariate analysis, age, smoking history, Controlling Nutritional Status score, depth of tumor invasion, pathological grade, and tumor diameter were related to the prognosis of patients with non-muscle invasive bladder cancer. On multivariate analysis, the Controlling Nutritional Status score (hazard ratio, 4.938; 95% confidence interval, 1.392-17.525; P = 0.013) was an independent factor affecting the recurrence-free survival of patients with non-muscle-invasive bladder cancer. Conclusion: Therefore, the Controlling Nutritional Status score could be a simple, cost-effective, and reliable predictor of prognoses among of patients with non-muscle-invasive bladder cancer.https://doi.org/10.1177/10732748211021078 |
spellingShingle | Jiaguo Huang MD Liwei Zhao MD Kai Wang MD Ji Sun MD Shengcheng Tai MD Runmiao Hua MD Yufu Yu MD Yi Fan MD Controlling Nutritional Status Score Evaluates Prognosis in Patients With Non-Muscle Invasive Bladder Cancer Cancer Control |
title | Controlling Nutritional Status Score Evaluates Prognosis in Patients With Non-Muscle Invasive Bladder Cancer |
title_full | Controlling Nutritional Status Score Evaluates Prognosis in Patients With Non-Muscle Invasive Bladder Cancer |
title_fullStr | Controlling Nutritional Status Score Evaluates Prognosis in Patients With Non-Muscle Invasive Bladder Cancer |
title_full_unstemmed | Controlling Nutritional Status Score Evaluates Prognosis in Patients With Non-Muscle Invasive Bladder Cancer |
title_short | Controlling Nutritional Status Score Evaluates Prognosis in Patients With Non-Muscle Invasive Bladder Cancer |
title_sort | controlling nutritional status score evaluates prognosis in patients with non muscle invasive bladder cancer |
url | https://doi.org/10.1177/10732748211021078 |
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