External Auditory Canal Mass: A Case Series of Squamous Cell Carcinoma
Introduction: Squamous cell carcinoma of the temporal bone is extremely rare comprising 0.2% of all tumors of head and neck. Symptoms are nonspecific and may be mistaken for other more benign conditions as otitis, cholesteatoma and polyp. Hence, this condition may present as a diagnostic challenge....
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| Format: | Article |
| Language: | English |
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West Asia Organization for Cancer Prevention
2023-02-01
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| Series: | Asian Pacific Journal of Cancer Care |
| Subjects: | |
| Online Access: | http://www.waocp.com/journal/index.php/apjcc/article/view/934 |
| _version_ | 1827370942065541120 |
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| author | Mel Valerie B. Cruz-Ordinario Edgar Christian S. Cuaresma Margarita D. Guevarra Elsie L. Lim Marcelo Severino B. Imasa |
| author_facet | Mel Valerie B. Cruz-Ordinario Edgar Christian S. Cuaresma Margarita D. Guevarra Elsie L. Lim Marcelo Severino B. Imasa |
| author_sort | Mel Valerie B. Cruz-Ordinario |
| collection | DOAJ |
| description | Introduction: Squamous cell carcinoma of the temporal bone is extremely rare comprising 0.2% of all tumors of head and neck. Symptoms are nonspecific and may be mistaken for other more benign conditions as otitis, cholesteatoma and polyp. Hence, this condition may present as a diagnostic challenge.
Case Discussion: We describe a case series of three patients who presented with external auditory canal (EAC) mass. The most common signs and symptoms are pruritus, decreased hearing and yellowish discharge. They were initially treated with otic antibiotics which afforded no relief. The first case is a 51 year-old female who underwent wide excision of the right ear canal and middle ear mass and right temporal craniotomy. Histopathology showed moderately differentiated squamous cell carcinoma with temporal tumor and subdural extension consistent with metastasis. The second case is a 53 year-old male who refused surgical management. He was non-compliant with work-up and follow-up and later on presented with left facial asymmetry and headache. CT scan showed a left inner and middle ear canal mass with extension to the auditory canal and protrusion into the left cerebellar hemisphere. Punch biopsy of the left EAC mass was done and pathologic report showed well-differentiated squamous cell carcinoma. Lastly, a 54 year old male who underwent Radical mastoidectomy with histopathology reports of a moderately differentiated squamous cell carcinoma.
Conclusion: Standard treatment modality is still unclear because of the rarity of this condition. However, surgical resection with negative margins followed by concurrent chemotherapy and radiation is the most commonly performed approach1. For the above-mentioned patients, concurrent chemotherapy and radiation therapy was given which showed significant treatment response. |
| first_indexed | 2024-03-08T10:30:54Z |
| format | Article |
| id | doaj.art-e59dbc73007a4ac293eb4abe349ddc9c |
| institution | Directory Open Access Journal |
| issn | 2588-3682 |
| language | English |
| last_indexed | 2024-03-08T10:30:54Z |
| publishDate | 2023-02-01 |
| publisher | West Asia Organization for Cancer Prevention |
| record_format | Article |
| series | Asian Pacific Journal of Cancer Care |
| spelling | doaj.art-e59dbc73007a4ac293eb4abe349ddc9c2024-01-27T06:39:01ZengWest Asia Organization for Cancer PreventionAsian Pacific Journal of Cancer Care2588-36822023-02-018120120610.31557/apjcc.2023.8.1.201-206934External Auditory Canal Mass: A Case Series of Squamous Cell CarcinomaMel Valerie B. Cruz-Ordinario0Edgar Christian S. Cuaresma1Margarita D. Guevarra2Elsie L. Lim3Marcelo Severino B. Imasa4St. Luke’s Medical Center, Consultant, Section of Medical Oncology, Quezon City, Philippines.St. Luke’s Medical Center, Consultant, Section of Medical Oncology, Quezon City, Philippines.St. Luke’s Medical Center, Consultant, Section of Medical Oncology, Quezon City, Philippines.St. Luke’s Medical Center, Consultant, Section of Medical Oncology, Quezon City, Philippines.St. Luke’s Medical Center, Consultant, Section of Medical Oncology, Quezon City, Philippines.Introduction: Squamous cell carcinoma of the temporal bone is extremely rare comprising 0.2% of all tumors of head and neck. Symptoms are nonspecific and may be mistaken for other more benign conditions as otitis, cholesteatoma and polyp. Hence, this condition may present as a diagnostic challenge. Case Discussion: We describe a case series of three patients who presented with external auditory canal (EAC) mass. The most common signs and symptoms are pruritus, decreased hearing and yellowish discharge. They were initially treated with otic antibiotics which afforded no relief. The first case is a 51 year-old female who underwent wide excision of the right ear canal and middle ear mass and right temporal craniotomy. Histopathology showed moderately differentiated squamous cell carcinoma with temporal tumor and subdural extension consistent with metastasis. The second case is a 53 year-old male who refused surgical management. He was non-compliant with work-up and follow-up and later on presented with left facial asymmetry and headache. CT scan showed a left inner and middle ear canal mass with extension to the auditory canal and protrusion into the left cerebellar hemisphere. Punch biopsy of the left EAC mass was done and pathologic report showed well-differentiated squamous cell carcinoma. Lastly, a 54 year old male who underwent Radical mastoidectomy with histopathology reports of a moderately differentiated squamous cell carcinoma. Conclusion: Standard treatment modality is still unclear because of the rarity of this condition. However, surgical resection with negative margins followed by concurrent chemotherapy and radiation is the most commonly performed approach1. For the above-mentioned patients, concurrent chemotherapy and radiation therapy was given which showed significant treatment response.http://www.waocp.com/journal/index.php/apjcc/article/view/934squamous cell carcinomaexternal auditory canal |
| spellingShingle | Mel Valerie B. Cruz-Ordinario Edgar Christian S. Cuaresma Margarita D. Guevarra Elsie L. Lim Marcelo Severino B. Imasa External Auditory Canal Mass: A Case Series of Squamous Cell Carcinoma Asian Pacific Journal of Cancer Care squamous cell carcinoma external auditory canal |
| title | External Auditory Canal Mass: A Case Series of Squamous Cell Carcinoma |
| title_full | External Auditory Canal Mass: A Case Series of Squamous Cell Carcinoma |
| title_fullStr | External Auditory Canal Mass: A Case Series of Squamous Cell Carcinoma |
| title_full_unstemmed | External Auditory Canal Mass: A Case Series of Squamous Cell Carcinoma |
| title_short | External Auditory Canal Mass: A Case Series of Squamous Cell Carcinoma |
| title_sort | external auditory canal mass a case series of squamous cell carcinoma |
| topic | squamous cell carcinoma external auditory canal |
| url | http://www.waocp.com/journal/index.php/apjcc/article/view/934 |
| work_keys_str_mv | AT melvaleriebcruzordinario externalauditorycanalmassacaseseriesofsquamouscellcarcinoma AT edgarchristianscuaresma externalauditorycanalmassacaseseriesofsquamouscellcarcinoma AT margaritadguevarra externalauditorycanalmassacaseseriesofsquamouscellcarcinoma AT elsiellim externalauditorycanalmassacaseseriesofsquamouscellcarcinoma AT marceloseverinobimasa externalauditorycanalmassacaseseriesofsquamouscellcarcinoma |