A prognostic and predictive computational pathology image signature for added benefit of adjuvant chemotherapy in early stage non-small-cell lung cancer

A prognostic and predictive computational pathology image signature for added benefit of adjuvant chemotherapy in early stage non-small-cell lung cancer

Background: We developed and validated a prognostic and predictive computational pathology risk score (CoRiS) using H&E stained tissue images from patients with early-stage non-small cell lung cancer (ES-NSCLC). Methods: 1330 patients with ES-NSCLC were acquired from 3 independent sources and di...

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Bibliographic Details
Main Authors: Xiangxue Wang, Kaustav Bera, Cristian Barrera, Yu Zhou, Cheng Lu, Pranjal Vaidya, Pingfu Fu, Michael Yang, Ralph Alexander Schmid, Sabina Berezowska, Humberto Choi, Vamsidhar Velcheti, Anant Madabhushi
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:EBioMedicine
Subjects:
Early-stage non-small cell lung cancer
Computational pathology
Prognostic and predictive
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421002747

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