Blood gas analysis in pigs submitted to different concentrations of nitrous oxide or oxygen, under different ventilatory modalities

ABSTRACT The effects of different concentrations of oxygen and nitrous oxide on blood gas parameters in pigs maintained under spontaneous or pressure-controlled ventilation, with or without positive end-expiratory pressure (PEEP), were compared. Forty-eight pigs were randomly divided into six groups...

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Main Authors: E.G.F. Biteli, N. Nunes, P.C.F. Lopes, P.E.S. Silva, C.K. Ido, H.R.A. Silva, M. Horr, R.L. Carneiro, T.F.V. Bompadre
Format: Article
Language:English
Published: Universidade Federal de Minas Gerais
Series:Arquivo Brasileiro de Medicina Veterinária e Zootecnia
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000100035&lng=en&tlng=en
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author E.G.F. Biteli
N. Nunes
P.C.F. Lopes
P.E.S. Silva
C.K. Ido
H.R.A. Silva
M. Horr
R.L. Carneiro
T.F.V. Bompadre
author_facet E.G.F. Biteli
N. Nunes
P.C.F. Lopes
P.E.S. Silva
C.K. Ido
H.R.A. Silva
M. Horr
R.L. Carneiro
T.F.V. Bompadre
author_sort E.G.F. Biteli
collection DOAJ
description ABSTRACT The effects of different concentrations of oxygen and nitrous oxide on blood gas parameters in pigs maintained under spontaneous or pressure-controlled ventilation, with or without positive end-expiratory pressure (PEEP), were compared. Forty-eight pigs were randomly divided into six groups, submitted to different concentrations of compressed air or N2O, associated with different fractions of inspired oxygen (FiO2). The group subject to 30% of compressed air (GA30) showed the closest proximity to the physiological range of partial pressure (PaO2) expected for the species. For oxygen saturation (SaO2), the values obtained were below the lower physiological limit in the group administered 30% N2O (GN30). Use of PEEP positively interfered in PaCO2 independent of FiO2, however, its effectiveness can be compromised when complemented by N2O-based anesthesia. For SaO2, only GN30 showed values lower than adequate for maintaining tissue oxygenation. The pH, base deficit and bicarbonate in arterial blood were influenced by FiO2 and N2O. In conclusion, the use of compressed air maintains blood gas parameters at their most stable, especially GA30 and PEEP, which seemed to positively influence the experimental groups, with some interference from FiO2 and N2O.
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spelling doaj.art-e5a0c8e57fb54246adde69c5030aa3152022-12-21T20:13:39ZengUniversidade Federal de Minas GeraisArquivo Brasileiro de Medicina Veterinária e Zootecnia1678-4162711354310.1590/1678-4162-10210S0102-09352019000100035Blood gas analysis in pigs submitted to different concentrations of nitrous oxide or oxygen, under different ventilatory modalitiesE.G.F. BiteliN. NunesP.C.F. LopesP.E.S. SilvaC.K. IdoH.R.A. SilvaM. HorrR.L. CarneiroT.F.V. BompadreABSTRACT The effects of different concentrations of oxygen and nitrous oxide on blood gas parameters in pigs maintained under spontaneous or pressure-controlled ventilation, with or without positive end-expiratory pressure (PEEP), were compared. Forty-eight pigs were randomly divided into six groups, submitted to different concentrations of compressed air or N2O, associated with different fractions of inspired oxygen (FiO2). The group subject to 30% of compressed air (GA30) showed the closest proximity to the physiological range of partial pressure (PaO2) expected for the species. For oxygen saturation (SaO2), the values obtained were below the lower physiological limit in the group administered 30% N2O (GN30). Use of PEEP positively interfered in PaCO2 independent of FiO2, however, its effectiveness can be compromised when complemented by N2O-based anesthesia. For SaO2, only GN30 showed values lower than adequate for maintaining tissue oxygenation. The pH, base deficit and bicarbonate in arterial blood were influenced by FiO2 and N2O. In conclusion, the use of compressed air maintains blood gas parameters at their most stable, especially GA30 and PEEP, which seemed to positively influence the experimental groups, with some interference from FiO2 and N2O.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000100035&lng=en&tlng=enalquilfenolatelectasiaporcosrespiração
spellingShingle E.G.F. Biteli
N. Nunes
P.C.F. Lopes
P.E.S. Silva
C.K. Ido
H.R.A. Silva
M. Horr
R.L. Carneiro
T.F.V. Bompadre
Blood gas analysis in pigs submitted to different concentrations of nitrous oxide or oxygen, under different ventilatory modalities
Arquivo Brasileiro de Medicina Veterinária e Zootecnia
alquilfenol
atelectasia
porcos
respiração
title Blood gas analysis in pigs submitted to different concentrations of nitrous oxide or oxygen, under different ventilatory modalities
title_full Blood gas analysis in pigs submitted to different concentrations of nitrous oxide or oxygen, under different ventilatory modalities
title_fullStr Blood gas analysis in pigs submitted to different concentrations of nitrous oxide or oxygen, under different ventilatory modalities
title_full_unstemmed Blood gas analysis in pigs submitted to different concentrations of nitrous oxide or oxygen, under different ventilatory modalities
title_short Blood gas analysis in pigs submitted to different concentrations of nitrous oxide or oxygen, under different ventilatory modalities
title_sort blood gas analysis in pigs submitted to different concentrations of nitrous oxide or oxygen under different ventilatory modalities
topic alquilfenol
atelectasia
porcos
respiração
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000100035&lng=en&tlng=en
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