Effect of different exercise regimens on LVEF and restenosis incidence in patients after PCI: a network meta-analysis and an overview of systematic reviews
ObjectiveWe aimed to evaluate the effects of different exercise rehabilitation (ER) programs on LVEF and the incidence of restenosis in patients after percutaneous coronary intervention (PCI) through a systematic review and an integrated network meta-analysis (NMA) to provide a reference for the cli...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-11-01
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| Series: | Frontiers in Cardiovascular Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1241343/full |
| _version_ | 1797627567662956544 |
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| author | Hongpeng Li Li Lu Zhongyu Han Zhixiang Liu Juanhong Pan Yongsheng Wang Xiuhua Gao Yijin Cai Tianyu Zhao Qian Nie Hongcai Zhang Di Zhang Song Jin |
| author_facet | Hongpeng Li Li Lu Zhongyu Han Zhixiang Liu Juanhong Pan Yongsheng Wang Xiuhua Gao Yijin Cai Tianyu Zhao Qian Nie Hongcai Zhang Di Zhang Song Jin |
| author_sort | Hongpeng Li |
| collection | DOAJ |
| description | ObjectiveWe aimed to evaluate the effects of different exercise rehabilitation (ER) programs on LVEF and the incidence of restenosis in patients after percutaneous coronary intervention (PCI) through a systematic review and an integrated network meta-analysis (NMA) to provide a reference for the clinical formulation of ER programs for PCI patients.MethodsMeta-analyses of the effects of different types of ER programs on LVEF and the incidence of reinfarction in post-PCI patients were retrieved from 11 domestic and foreign databases. The methodological and reporting quality of the included systematic reviews were evaluated using the AMSTAR 2 and PRISMA statements. The GRADE scoring system was used to evaluate the quality of evidence found in the studies included in the meta-analysis, and studies with high and intermediate-quality evidence were qualitatively analyzed. Stata software (version 16.0) was used to conduct an integrated NMA of the original RCTs with moderate and low risk of bias.ResultSixteen meta-analyses were included in this evaluation. The reporting quality of the included meta-analyses was relatively complete, and the methodological quality was low. Seventy RCTs were included in the NMA. The results showed that all types of rehabilitative exercises were safe and effectively increased LVEF and reduced the incidence of coronary restenosis in patients. The comprehensive exercise program was the most likely to improve LVEF, and the comprehensive exercise program, early exercise program, and high-intensity interval exercise were better than aerobic exercise. Comprehensive exercise programs, early exercise programs, and aerobic exercise reduced the incidence of restenosis in patients. However, Chinese Qigong did not reduce the incidence of restenosis in patients, and there was a risk of bias and inconsistency in the quantitative analysis of restenosis incidence.ConclusionComprehensive exercise programs have the greatest therapeutic significance in improving cardiac output and reducing restenosis rates in post-PCI patients. The early exercise program has great potential but requires kinesiologists to work with physicians to structure the program and strengthen out-of-hospital management. Aerobic exercise has the least therapeutic significance, and Chinese Qigong is suitable for promotion based on its better efficacy than aerobic exercise and may be an alternative to aerobic exercise, but more experimental evidence is needed.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/, PROSPERO CRD42022374590. |
| first_indexed | 2024-03-11T10:26:10Z |
| format | Article |
| id | doaj.art-e5a0cdc68a0d4b19adf6a8f97a893f30 |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-03-11T10:26:10Z |
| publishDate | 2023-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-e5a0cdc68a0d4b19adf6a8f97a893f302023-11-15T14:29:24ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2023-11-011010.3389/fcvm.2023.12413431241343Effect of different exercise regimens on LVEF and restenosis incidence in patients after PCI: a network meta-analysis and an overview of systematic reviewsHongpeng Li0Li Lu1Zhongyu Han2Zhixiang Liu3Juanhong Pan4Yongsheng Wang5Xiuhua Gao6Yijin Cai7Tianyu Zhao8Qian Nie9Hongcai Zhang10Di Zhang11Song Jin12School of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaSchool of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaSchool of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaSchool of Health Preservation and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaSchool of Health Preservation and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaSchool of Health Preservation and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaDepartment of Rehabilitation, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaSchool of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaDepartment of Rehabilitation, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaSecond Department of Cardiology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaSecond Department of Cardiology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaDepartment of Rehabilitation, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaDepartment of Rehabilitation, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaObjectiveWe aimed to evaluate the effects of different exercise rehabilitation (ER) programs on LVEF and the incidence of restenosis in patients after percutaneous coronary intervention (PCI) through a systematic review and an integrated network meta-analysis (NMA) to provide a reference for the clinical formulation of ER programs for PCI patients.MethodsMeta-analyses of the effects of different types of ER programs on LVEF and the incidence of reinfarction in post-PCI patients were retrieved from 11 domestic and foreign databases. The methodological and reporting quality of the included systematic reviews were evaluated using the AMSTAR 2 and PRISMA statements. The GRADE scoring system was used to evaluate the quality of evidence found in the studies included in the meta-analysis, and studies with high and intermediate-quality evidence were qualitatively analyzed. Stata software (version 16.0) was used to conduct an integrated NMA of the original RCTs with moderate and low risk of bias.ResultSixteen meta-analyses were included in this evaluation. The reporting quality of the included meta-analyses was relatively complete, and the methodological quality was low. Seventy RCTs were included in the NMA. The results showed that all types of rehabilitative exercises were safe and effectively increased LVEF and reduced the incidence of coronary restenosis in patients. The comprehensive exercise program was the most likely to improve LVEF, and the comprehensive exercise program, early exercise program, and high-intensity interval exercise were better than aerobic exercise. Comprehensive exercise programs, early exercise programs, and aerobic exercise reduced the incidence of restenosis in patients. However, Chinese Qigong did not reduce the incidence of restenosis in patients, and there was a risk of bias and inconsistency in the quantitative analysis of restenosis incidence.ConclusionComprehensive exercise programs have the greatest therapeutic significance in improving cardiac output and reducing restenosis rates in post-PCI patients. The early exercise program has great potential but requires kinesiologists to work with physicians to structure the program and strengthen out-of-hospital management. Aerobic exercise has the least therapeutic significance, and Chinese Qigong is suitable for promotion based on its better efficacy than aerobic exercise and may be an alternative to aerobic exercise, but more experimental evidence is needed.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/, PROSPERO CRD42022374590.https://www.frontiersin.org/articles/10.3389/fcvm.2023.1241343/fullPCIsports medicineexercise rehabilitationmeta-analysiscoronary heart |
| spellingShingle | Hongpeng Li Li Lu Zhongyu Han Zhixiang Liu Juanhong Pan Yongsheng Wang Xiuhua Gao Yijin Cai Tianyu Zhao Qian Nie Hongcai Zhang Di Zhang Song Jin Effect of different exercise regimens on LVEF and restenosis incidence in patients after PCI: a network meta-analysis and an overview of systematic reviews Frontiers in Cardiovascular Medicine PCI sports medicine exercise rehabilitation meta-analysis coronary heart |
| title | Effect of different exercise regimens on LVEF and restenosis incidence in patients after PCI: a network meta-analysis and an overview of systematic reviews |
| title_full | Effect of different exercise regimens on LVEF and restenosis incidence in patients after PCI: a network meta-analysis and an overview of systematic reviews |
| title_fullStr | Effect of different exercise regimens on LVEF and restenosis incidence in patients after PCI: a network meta-analysis and an overview of systematic reviews |
| title_full_unstemmed | Effect of different exercise regimens on LVEF and restenosis incidence in patients after PCI: a network meta-analysis and an overview of systematic reviews |
| title_short | Effect of different exercise regimens on LVEF and restenosis incidence in patients after PCI: a network meta-analysis and an overview of systematic reviews |
| title_sort | effect of different exercise regimens on lvef and restenosis incidence in patients after pci a network meta analysis and an overview of systematic reviews |
| topic | PCI sports medicine exercise rehabilitation meta-analysis coronary heart |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1241343/full |
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