Balancing selection on a regulatory region exhibiting ancient variation that predates human-neandertal divergence.

Ancient population structure shaping contemporary genetic variation has been recently appreciated and has important implications regarding our understanding of the structure of modern human genomes. We identified a ∼36-kb DNA segment in the human genome that displays an ancient substructure. The var...

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Bibliografiska uppgifter
Huvudupphovsmän: Omer Gokcumen, Qihui Zhu, Lubbertus C F Mulder, Rebecca C Iskow, Christian Austermann, Christopher D Scharer, Towfique Raj, Jeremy M Boss, Shamil Sunyaev, Alkes Price, Barbara Stranger, Viviana Simon, Charles Lee
Materialtyp: Artikel
Språk:English
Publicerad: Public Library of Science (PLoS) 2013-04-01
Serie:PLoS Genetics
Länkar:http://europepmc.org/articles/PMC3623772?pdf=render