Multiplying the heterologous production of spinosad through tandem amplification of its biosynthetic gene cluster in Streptomyces coelicolor

Summary Heterologous expression of the biosynthetic gene cluster (BGC) is important for studying the microbial natural products (NPs), especially for those kept in silent or poorly expressed in their original strains. Here, we cloned the spinosad BGC through the Cas9‐Assisted Targeting of Chromosome...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Hong Li, Yuanyuan Pan, Gang Liu
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Wiley 2022-05-01
Sraith:Microbial Biotechnology
Rochtain ar líne:https://doi.org/10.1111/1751-7915.13965