In vivo evolution of drug-resistant Mycobacterium tuberculosis in patients during long-term treatment

In vivo evolution of drug-resistant Mycobacterium tuberculosis in patients during long-term treatment

Abstract Background In the current scenario, the drug-resistant tuberculosis is a significant challenge in the control of tuberculosis worldwide. In order to investigate the in vivo evolution of drug-resistant M. tuberculosis, the present study envisaged sequencing of the draft genomes of 18 serial...

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Bibliographic Details
Main Authors: Yuhui Xu, Fei Liu, Suting Chen, Jiannan Wu, Yongfei Hu, Baoli Zhu, Zhaogang Sun
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Genomics
Subjects:
Drug-resistant tuberculosis
Treatment
Genetic changes
SNP
Online Access:http://link.springer.com/article/10.1186/s12864-018-5010-5

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