The Impact of Frailty and Comorbidities on Heart Failure Outcomes
Frailty is a multisystemic process leading to reduction of physiological reserve and a reduction in physical activity. Heart failure (HF) is recognised as a global cause of morbidity and mortality, increasing in prevalence over recent decades. Because of shared phenotypes and comorbidities, there is...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Radcliffe Medical Media
2022-03-01
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| Series: | Cardiac Failure Review |
| Online Access: | https://www.cfrjournal.com/articleindex/cfr.2021.29 |
| _version_ | 1797200016799956992 |
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| author | Thomas Salmon Hani Essa Behnam Tajik Masoud Isanejad Asangaedem Akpan Rajiv Sankaranarayanan |
| author_facet | Thomas Salmon Hani Essa Behnam Tajik Masoud Isanejad Asangaedem Akpan Rajiv Sankaranarayanan |
| author_sort | Thomas Salmon |
| collection | DOAJ |
| description | Frailty is a multisystemic process leading to reduction of physiological reserve and a reduction in physical activity. Heart failure (HF) is recognised as a global cause of morbidity and mortality, increasing in prevalence over recent decades. Because of shared phenotypes and comorbidities, there is significant overlap and a bidirectional relationship, with frail patients being at increased risk of developing HF and vice versa. Despite this, frailty is not routinely assessed in patients with HF. Identification of these patients to direct multidisciplinary care is key, and the development of a frailty assessment tool validated in a large HF population is also an unmet need that would be of considerable benefit in directing multidisciplinary-team management. Non-pharmacological treatment should be included, as exercise and physical rehabilitation programmes offer dual benefit in frail HF patients, by treating both conditions simultaneously. The evidence for nutritional supplementation is mixed, but there is evidence that a personalised approach to nutritional support in frail HF patients can improve outcomes. |
| first_indexed | 2024-03-07T17:40:25Z |
| format | Article |
| id | doaj.art-e5a7904490e4454f96b1112cdb817d90 |
| institution | Directory Open Access Journal |
| issn | 2057-7540 2057-7559 |
| language | English |
| last_indexed | 2024-04-24T07:24:57Z |
| publishDate | 2022-03-01 |
| publisher | Radcliffe Medical Media |
| record_format | Article |
| series | Cardiac Failure Review |
| spelling | doaj.art-e5a7904490e4454f96b1112cdb817d902024-04-20T16:02:45ZengRadcliffe Medical MediaCardiac Failure Review2057-75402057-75592022-03-01810.15420/cfr.2021.29The Impact of Frailty and Comorbidities on Heart Failure OutcomesThomas Salmon0Hani Essa1Behnam TajikMasoud Isanejad2Asangaedem Akpan3Rajiv Sankaranarayanan4Department of Cardiology, Aintree University Hospital, Liverpool University Hospitals NHS Foundation Trust, Liverpool UKDepartment of Cardiology, Aintree University Hospital, Liverpool University Hospitals NHS Foundation Trust, Liverpool UK; Liverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool Heart & Chest Hospital, Liverpool, UKLiverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool Heart & Chest Hospital, Liverpool, UK; Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool UKDepartment of Cardiology, Aintree University Hospital, Liverpool University Hospitals NHS Foundation Trust, Liverpool UK; Liverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool Heart & Chest Hospital, Liverpool, UKDepartment of Cardiology, Aintree University Hospital, Liverpool University Hospitals NHS Foundation Trust, Liverpool UK; Liverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool Heart & Chest Hospital, Liverpool, UK; National Institute for Health Research, UKFrailty is a multisystemic process leading to reduction of physiological reserve and a reduction in physical activity. Heart failure (HF) is recognised as a global cause of morbidity and mortality, increasing in prevalence over recent decades. Because of shared phenotypes and comorbidities, there is significant overlap and a bidirectional relationship, with frail patients being at increased risk of developing HF and vice versa. Despite this, frailty is not routinely assessed in patients with HF. Identification of these patients to direct multidisciplinary care is key, and the development of a frailty assessment tool validated in a large HF population is also an unmet need that would be of considerable benefit in directing multidisciplinary-team management. Non-pharmacological treatment should be included, as exercise and physical rehabilitation programmes offer dual benefit in frail HF patients, by treating both conditions simultaneously. The evidence for nutritional supplementation is mixed, but there is evidence that a personalised approach to nutritional support in frail HF patients can improve outcomes.https://www.cfrjournal.com/articleindex/cfr.2021.29 |
| spellingShingle | Thomas Salmon Hani Essa Behnam Tajik Masoud Isanejad Asangaedem Akpan Rajiv Sankaranarayanan The Impact of Frailty and Comorbidities on Heart Failure Outcomes Cardiac Failure Review |
| title | The Impact of Frailty and Comorbidities on Heart Failure Outcomes |
| title_full | The Impact of Frailty and Comorbidities on Heart Failure Outcomes |
| title_fullStr | The Impact of Frailty and Comorbidities on Heart Failure Outcomes |
| title_full_unstemmed | The Impact of Frailty and Comorbidities on Heart Failure Outcomes |
| title_short | The Impact of Frailty and Comorbidities on Heart Failure Outcomes |
| title_sort | impact of frailty and comorbidities on heart failure outcomes |
| url | https://www.cfrjournal.com/articleindex/cfr.2021.29 |
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