ANTIBACTERIAL ACTIVITY OF BASIL LEAVES EXTRACT TOWARDS BACTERIA STAPHYLOCOCCUS AUREUS AND STAPHYLOCOCCUS EPIDERMIDIS IN DEODORANT SPRAY

Body odor is a significant problem and is often encountered in some individuals characterized by excessive odor. A deodorant spray made from basil leaf (Ocimum Basilicum L.) extract is a product used to treat body odor caused by Staphylococcus Aureus and Staphylococcus epidermidis bacteria. The pur...

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Main Authors: Tetty Noverita Khairani, Khairani Fitri, Muhammad Andry, Muhammad Amin Nasution
Format: Article
Language:Indonesian
Published: Universitas Muhammadiyah Magelang 2023-12-01
Series:Jurnal Farmasi Sains dan Praktis
Subjects:
Online Access:https://journal.unimma.ac.id/index.php/pharmacy/article/view/7542
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author Tetty Noverita Khairani
Khairani Fitri
Muhammad Andry
Muhammad Amin Nasution
author_facet Tetty Noverita Khairani
Khairani Fitri
Muhammad Andry
Muhammad Amin Nasution
author_sort Tetty Noverita Khairani
collection DOAJ
description Body odor is a significant problem and is often encountered in some individuals characterized by excessive odor. A deodorant spray made from basil leaf (Ocimum Basilicum L.) extract is a product used to treat body odor caused by Staphylococcus Aureus and Staphylococcus epidermidis bacteria. The purpose of this study is to assess the efficacy of deodorant spray and basil leaf extract on bacterial activity, as well as the optimal dose of deodorant spray for lowering the activity of these bacteria. Method the research was conducted experimentally, testing antibacterial activity using agar diffusion. The results of the deodorant spray preparation test showed that the preparation was homogeneous, organoleptically brown in color, had a distinctive smell, and had a liquid texture; the pH test results met the requirements for deodorant spray 4.5-6.5. The average diameter of the inhibition zones produced from each preparation were Staphylococcus epidermidis bacteria, positive control 7 mm, negative control 10.1 mm; formula 5% 12.3 mm; formula 10% 13.3 mm; formula 15% 12.7 mm maximum concentration in inhibiting bacteria is formula 10% by 13.3 mm, while the bacteria Staphylococcus Aureus positive control 13 mm, negative control 11.2 mm, 5% formula 13.1 mm; formula 10% 13.4 mm; 15% formula 13.9 mm maximum concentration in inhibiting bacteria is 15% formula 13.9 mm. Based on the inhibitory zone created by 10% basil leaf ethanol extract, Staphylococcus epidermidis bacteria had a 13.3 mm clean zone and Staphylococcus aureus bacteria had a 26.5 mm clean zone.
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spelling doaj.art-e5aa934deff74a48a60922035a9ea8562023-12-28T05:19:42ZindUniversitas Muhammadiyah MagelangJurnal Farmasi Sains dan Praktis2549-90682579-45582023-12-019310.31603/pharmacy.v9i3.7542ANTIBACTERIAL ACTIVITY OF BASIL LEAVES EXTRACT TOWARDS BACTERIA STAPHYLOCOCCUS AUREUS AND STAPHYLOCOCCUS EPIDERMIDIS IN DEODORANT SPRAYTetty Noverita Khairani0Khairani Fitri1Muhammad Andry2Muhammad Amin Nasution3Department of Pharmaceutical Biology, Faculty of Pharmacy, Institut Kesehatan Helvetia, Medan 20124, IndonesiaDepartment of Pharmaceutical Biology, Faculty of Pharmacy, Institut Kesehatan Helvetia, Medan 20124, IndonesiaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Institut Kesehatan Helvetia, Medan 20124, IndonesiaFaculty of Pharmacy, Universitas Muslim Nusantara Al Washliyah, Medan 20147, Indonesia Body odor is a significant problem and is often encountered in some individuals characterized by excessive odor. A deodorant spray made from basil leaf (Ocimum Basilicum L.) extract is a product used to treat body odor caused by Staphylococcus Aureus and Staphylococcus epidermidis bacteria. The purpose of this study is to assess the efficacy of deodorant spray and basil leaf extract on bacterial activity, as well as the optimal dose of deodorant spray for lowering the activity of these bacteria. Method the research was conducted experimentally, testing antibacterial activity using agar diffusion. The results of the deodorant spray preparation test showed that the preparation was homogeneous, organoleptically brown in color, had a distinctive smell, and had a liquid texture; the pH test results met the requirements for deodorant spray 4.5-6.5. The average diameter of the inhibition zones produced from each preparation were Staphylococcus epidermidis bacteria, positive control 7 mm, negative control 10.1 mm; formula 5% 12.3 mm; formula 10% 13.3 mm; formula 15% 12.7 mm maximum concentration in inhibiting bacteria is formula 10% by 13.3 mm, while the bacteria Staphylococcus Aureus positive control 13 mm, negative control 11.2 mm, 5% formula 13.1 mm; formula 10% 13.4 mm; 15% formula 13.9 mm maximum concentration in inhibiting bacteria is 15% formula 13.9 mm. Based on the inhibitory zone created by 10% basil leaf ethanol extract, Staphylococcus epidermidis bacteria had a 13.3 mm clean zone and Staphylococcus aureus bacteria had a 26.5 mm clean zone. https://journal.unimma.ac.id/index.php/pharmacy/article/view/7542Deodorant sprayOcimum basilicumStaphylococcus EpidermidisStaphylococcus Aureus
spellingShingle Tetty Noverita Khairani
Khairani Fitri
Muhammad Andry
Muhammad Amin Nasution
ANTIBACTERIAL ACTIVITY OF BASIL LEAVES EXTRACT TOWARDS BACTERIA STAPHYLOCOCCUS AUREUS AND STAPHYLOCOCCUS EPIDERMIDIS IN DEODORANT SPRAY
Jurnal Farmasi Sains dan Praktis
Deodorant spray
Ocimum basilicum
Staphylococcus Epidermidis
Staphylococcus Aureus
title ANTIBACTERIAL ACTIVITY OF BASIL LEAVES EXTRACT TOWARDS BACTERIA STAPHYLOCOCCUS AUREUS AND STAPHYLOCOCCUS EPIDERMIDIS IN DEODORANT SPRAY
title_full ANTIBACTERIAL ACTIVITY OF BASIL LEAVES EXTRACT TOWARDS BACTERIA STAPHYLOCOCCUS AUREUS AND STAPHYLOCOCCUS EPIDERMIDIS IN DEODORANT SPRAY
title_fullStr ANTIBACTERIAL ACTIVITY OF BASIL LEAVES EXTRACT TOWARDS BACTERIA STAPHYLOCOCCUS AUREUS AND STAPHYLOCOCCUS EPIDERMIDIS IN DEODORANT SPRAY
title_full_unstemmed ANTIBACTERIAL ACTIVITY OF BASIL LEAVES EXTRACT TOWARDS BACTERIA STAPHYLOCOCCUS AUREUS AND STAPHYLOCOCCUS EPIDERMIDIS IN DEODORANT SPRAY
title_short ANTIBACTERIAL ACTIVITY OF BASIL LEAVES EXTRACT TOWARDS BACTERIA STAPHYLOCOCCUS AUREUS AND STAPHYLOCOCCUS EPIDERMIDIS IN DEODORANT SPRAY
title_sort antibacterial activity of basil leaves extract towards bacteria staphylococcus aureus and staphylococcus epidermidis in deodorant spray
topic Deodorant spray
Ocimum basilicum
Staphylococcus Epidermidis
Staphylococcus Aureus
url https://journal.unimma.ac.id/index.php/pharmacy/article/view/7542
work_keys_str_mv AT tettynoveritakhairani antibacterialactivityofbasilleavesextracttowardsbacteriastaphylococcusaureusandstaphylococcusepidermidisindeodorantspray
AT khairanifitri antibacterialactivityofbasilleavesextracttowardsbacteriastaphylococcusaureusandstaphylococcusepidermidisindeodorantspray
AT muhammadandry antibacterialactivityofbasilleavesextracttowardsbacteriastaphylococcusaureusandstaphylococcusepidermidisindeodorantspray
AT muhammadaminnasution antibacterialactivityofbasilleavesextracttowardsbacteriastaphylococcusaureusandstaphylococcusepidermidisindeodorantspray