Electrochemical C−C bond cleavage of cyclopropanes towards the synthesis of 1,3-difunctionalized molecules
Electrochemical oxidative C–C bond cleavage and functionalization are rarely developed due to the inertness and weak electronic bias of C–C bonds. In this study, the authors report the electrochemical C–C bond cleavage and 1,3-difluorination, 1,3-oxyfluorination and 1,3-dioxygenation of arylcyclopro...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-23401-8 |
| _version_ | 1818834910611243008 |
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| author | Pan Peng Xingxiu Yan Ke Zhang Zhao Liu Li Zeng Yixuan Chen Heng Zhang Aiwen Lei |
| author_facet | Pan Peng Xingxiu Yan Ke Zhang Zhao Liu Li Zeng Yixuan Chen Heng Zhang Aiwen Lei |
| author_sort | Pan Peng |
| collection | DOAJ |
| description | Electrochemical oxidative C–C bond cleavage and functionalization are rarely developed due to the inertness and weak electronic bias of C–C bonds. In this study, the authors report the electrochemical C–C bond cleavage and 1,3-difluorination, 1,3-oxyfluorination and 1,3-dioxygenation of arylcyclopropanes under catalyst-free and external-oxidant-free conditions. |
| first_indexed | 2024-12-19T02:42:20Z |
| format | Article |
| id | doaj.art-e5ab8ed784c04acdb07230676828ba79 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-19T02:42:20Z |
| publishDate | 2021-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-e5ab8ed784c04acdb07230676828ba792022-12-21T20:39:07ZengNature PortfolioNature Communications2041-17232021-05-011211710.1038/s41467-021-23401-8Electrochemical C−C bond cleavage of cyclopropanes towards the synthesis of 1,3-difunctionalized moleculesPan Peng0Xingxiu Yan1Ke Zhang2Zhao Liu3Li Zeng4Yixuan Chen5Heng Zhang6Aiwen Lei7The Institute for Advanced Studies (IAS), College of Chemistry and Molecular Sciences, Wuhan UniversityThe Institute for Advanced Studies (IAS), College of Chemistry and Molecular Sciences, Wuhan UniversityThe Institute for Advanced Studies (IAS), College of Chemistry and Molecular Sciences, Wuhan UniversityThe Institute for Advanced Studies (IAS), College of Chemistry and Molecular Sciences, Wuhan UniversityThe Institute for Advanced Studies (IAS), College of Chemistry and Molecular Sciences, Wuhan UniversityThe Institute for Advanced Studies (IAS), College of Chemistry and Molecular Sciences, Wuhan UniversityThe Institute for Advanced Studies (IAS), College of Chemistry and Molecular Sciences, Wuhan UniversityThe Institute for Advanced Studies (IAS), College of Chemistry and Molecular Sciences, Wuhan UniversityElectrochemical oxidative C–C bond cleavage and functionalization are rarely developed due to the inertness and weak electronic bias of C–C bonds. In this study, the authors report the electrochemical C–C bond cleavage and 1,3-difluorination, 1,3-oxyfluorination and 1,3-dioxygenation of arylcyclopropanes under catalyst-free and external-oxidant-free conditions.https://doi.org/10.1038/s41467-021-23401-8 |
| spellingShingle | Pan Peng Xingxiu Yan Ke Zhang Zhao Liu Li Zeng Yixuan Chen Heng Zhang Aiwen Lei Electrochemical C−C bond cleavage of cyclopropanes towards the synthesis of 1,3-difunctionalized molecules Nature Communications |
| title | Electrochemical C−C bond cleavage of cyclopropanes towards the synthesis of 1,3-difunctionalized molecules |
| title_full | Electrochemical C−C bond cleavage of cyclopropanes towards the synthesis of 1,3-difunctionalized molecules |
| title_fullStr | Electrochemical C−C bond cleavage of cyclopropanes towards the synthesis of 1,3-difunctionalized molecules |
| title_full_unstemmed | Electrochemical C−C bond cleavage of cyclopropanes towards the synthesis of 1,3-difunctionalized molecules |
| title_short | Electrochemical C−C bond cleavage of cyclopropanes towards the synthesis of 1,3-difunctionalized molecules |
| title_sort | electrochemical c c bond cleavage of cyclopropanes towards the synthesis of 1 3 difunctionalized molecules |
| url | https://doi.org/10.1038/s41467-021-23401-8 |
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