Human T-cell lymphotropic virus type 1 (HTLV-1)-associated bronchioloalveolar disorder required differentiation from fibrotic chronic hypersensitivity pneumonitis
We encountered a case of HTLV-1-associated bronchioloalveolar disorder (HABA) that was difficult to distinguish from fibrotic chronic hypersensitivity pneumonitis (CHP). Chest thin-section computed tomography (CT) showed diffuse micronodules and revealed peribronchovascular and perilobular distribut...
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Elsevier
2022-07-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043322002825 |
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| author | Tomonori Chikasue, MD Akiko Sumi, MD, PhD Shuichi Tanoue, MD, PhD Toshi Abe, MD, PhD Masaki Tominaga, MD, PhD Junya Fukuoka, MD, PhD Kiminori Fujimoto, MD, PhD |
| author_facet | Tomonori Chikasue, MD Akiko Sumi, MD, PhD Shuichi Tanoue, MD, PhD Toshi Abe, MD, PhD Masaki Tominaga, MD, PhD Junya Fukuoka, MD, PhD Kiminori Fujimoto, MD, PhD |
| author_sort | Tomonori Chikasue, MD |
| collection | DOAJ |
| description | We encountered a case of HTLV-1-associated bronchioloalveolar disorder (HABA) that was difficult to distinguish from fibrotic chronic hypersensitivity pneumonitis (CHP). Chest thin-section computed tomography (CT) showed diffuse micronodules and revealed peribronchovascular and perilobular distribution. Further, thickening of the interlobular septa, areas of ground-glass attenuation, traction bronchiectasis/bronchiolectasis, and air trapping were observed. Based on these findings, diseases that cause lymphatic tract abnormalities and fibrotic CHP were considered differential diseases. A surgical lung biopsy was performed, and an HTLV-1 antibody was detected using the Western blot analysis of bronchoalveolar lavage fluid. The final diagnosis of HABA was made through a multidisciplinary discussion. |
| first_indexed | 2024-04-13T22:02:39Z |
| format | Article |
| id | doaj.art-e5ae763257ca448589343398462497a2 |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-04-13T22:02:39Z |
| publishDate | 2022-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-e5ae763257ca448589343398462497a22022-12-22T02:28:03ZengElsevierRadiology Case Reports1930-04332022-07-0117724482452Human T-cell lymphotropic virus type 1 (HTLV-1)-associated bronchioloalveolar disorder required differentiation from fibrotic chronic hypersensitivity pneumonitisTomonori Chikasue, MD0Akiko Sumi, MD, PhD1Shuichi Tanoue, MD, PhD2Toshi Abe, MD, PhD3Masaki Tominaga, MD, PhD4Junya Fukuoka, MD, PhD5Kiminori Fujimoto, MD, PhD6Department of Radiology, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka, 830-0011, Japan; Corresponding author.Department of Radiology, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka, 830-0011, JapanDepartment of Radiology, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka, 830-0011, JapanDepartment of Radiology, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka, 830-0011, JapanDivision of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka, JapanDepartment of Pathology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, JapanDepartment of Radiology, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka, 830-0011, JapanWe encountered a case of HTLV-1-associated bronchioloalveolar disorder (HABA) that was difficult to distinguish from fibrotic chronic hypersensitivity pneumonitis (CHP). Chest thin-section computed tomography (CT) showed diffuse micronodules and revealed peribronchovascular and perilobular distribution. Further, thickening of the interlobular septa, areas of ground-glass attenuation, traction bronchiectasis/bronchiolectasis, and air trapping were observed. Based on these findings, diseases that cause lymphatic tract abnormalities and fibrotic CHP were considered differential diseases. A surgical lung biopsy was performed, and an HTLV-1 antibody was detected using the Western blot analysis of bronchoalveolar lavage fluid. The final diagnosis of HABA was made through a multidisciplinary discussion.http://www.sciencedirect.com/science/article/pii/S1930043322002825HTVL-1 (Human T-cell leukemia virus type 1)HABA (HTLV-1-associated bronchioloalveolar disorder)CHP (chronic hypersensitivity pneumonitis)Fibrotic hypersensitivity pneumonitisThin-section CT |
| spellingShingle | Tomonori Chikasue, MD Akiko Sumi, MD, PhD Shuichi Tanoue, MD, PhD Toshi Abe, MD, PhD Masaki Tominaga, MD, PhD Junya Fukuoka, MD, PhD Kiminori Fujimoto, MD, PhD Human T-cell lymphotropic virus type 1 (HTLV-1)-associated bronchioloalveolar disorder required differentiation from fibrotic chronic hypersensitivity pneumonitis Radiology Case Reports HTVL-1 (Human T-cell leukemia virus type 1) HABA (HTLV-1-associated bronchioloalveolar disorder) CHP (chronic hypersensitivity pneumonitis) Fibrotic hypersensitivity pneumonitis Thin-section CT |
| title | Human T-cell lymphotropic virus type 1 (HTLV-1)-associated bronchioloalveolar disorder required differentiation from fibrotic chronic hypersensitivity pneumonitis |
| title_full | Human T-cell lymphotropic virus type 1 (HTLV-1)-associated bronchioloalveolar disorder required differentiation from fibrotic chronic hypersensitivity pneumonitis |
| title_fullStr | Human T-cell lymphotropic virus type 1 (HTLV-1)-associated bronchioloalveolar disorder required differentiation from fibrotic chronic hypersensitivity pneumonitis |
| title_full_unstemmed | Human T-cell lymphotropic virus type 1 (HTLV-1)-associated bronchioloalveolar disorder required differentiation from fibrotic chronic hypersensitivity pneumonitis |
| title_short | Human T-cell lymphotropic virus type 1 (HTLV-1)-associated bronchioloalveolar disorder required differentiation from fibrotic chronic hypersensitivity pneumonitis |
| title_sort | human t cell lymphotropic virus type 1 htlv 1 associated bronchioloalveolar disorder required differentiation from fibrotic chronic hypersensitivity pneumonitis |
| topic | HTVL-1 (Human T-cell leukemia virus type 1) HABA (HTLV-1-associated bronchioloalveolar disorder) CHP (chronic hypersensitivity pneumonitis) Fibrotic hypersensitivity pneumonitis Thin-section CT |
| url | http://www.sciencedirect.com/science/article/pii/S1930043322002825 |
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