Noninvasive 40-Hz Light Flicker Rescues Circadian Behavior and Abnormal Lipid Metabolism Induced by Acute Ethanol Exposure via Improving SIRT1 and the Circadian Clock in the Liver-Brain Axis

Noninvasive 40-Hz Light Flicker Rescues Circadian Behavior and Abnormal Lipid Metabolism Induced by Acute Ethanol Exposure via Improving SIRT1 and the Circadian Clock in the Liver-Brain Axis

Sirtuin 1 (SIRT1) is a protein deacetylase with important cellular functions, as it regulates numerous processes, including the circadian rhythm in peripheral tissues. Efforts are ongoing to reveal how Sirt1 can be used to treat diseases, such as alcoholic liver disease (ALD), Alzheimer's disea...

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Bibliographic Details
Main Authors: Youli Yao, Wenjiang Zhang, Ruibo Ming, Qiyu Deng, Along Zuo, Shengli Zhang, Ying Ying, Yingying Zhao, Junxian Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Pharmacology
Subjects:
40-Hz light flicker
sirtuin 1
circadian clock
alcoholic liver steatosis
suprachiasmatic nucleus
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00355/full

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