Mathematical modeling links Wnt signaling to emergent patterns of metabolism in colon cancer
Abstract Cell‐intrinsic metabolic reprogramming is a hallmark of cancer that provides anabolic support to cell proliferation. How reprogramming influences tumor heterogeneity or drug sensitivities is not well understood. Here, we report a self‐organizing spatial pattern of glycolysis in xenograft co...
Main Authors: | Mary Lee, George T Chen, Eric Puttock, Kehui Wang, Robert A Edwards, Marian L Waterman, John Lowengrub |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2017-02-01
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Series: | Molecular Systems Biology |
Subjects: | |
Online Access: | https://doi.org/10.15252/msb.20167386 |
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