Eupatilin Ameliorates Hepatic Fibrosis and Hepatic Stellate Cell Activation by Suppressing β-catenin/PAI-1 Pathway

Eupatilin Ameliorates Hepatic Fibrosis and Hepatic Stellate Cell Activation by Suppressing β-catenin/PAI-1 Pathway

The activation of hepatic stellate cells (HSCs) has proved to be pivotal in hepatic fibrosis. Therefore, the suppression of HSC activation is an effective anti-fibrotic strategy. Although studies have indicated that eupatilin, a bioactive flavone found in <i>Artemisia argyi</i>, has anti...

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Bibliographic Details
Main Authors: Jinyuan Hu, Yuanyuan Liu, Zheng Pan, Xuekuan Huang, Jianwei Wang, Wenfu Cao, Zhiwei Chen
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
eupatilin
hepatic fibrosis
HSC
EMT
β-catenin
PAI-1
Online Access:https://www.mdpi.com/1422-0067/24/6/5933

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https://www.mdpi.com/1422-0067/24/6/5933

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