Distributed processing for value-based choice by prelimbic circuits targeting anterior-posterior dorsal striatal subregions in male mice

The prelimbic region of the prefrontal cortex is involved in goal-directed action. Here the authors investigate the function of the prelimbic pathways projecting along the anterior posterior striatal axis in value based decision making in male mice.

Bibliographic Details
Main Authors: Kyuhyun Choi, Eugenio Piasini, Edgar Díaz-Hernández, Luigim Vargas Cifuentes, Nathan T. Henderson, Elizabeth N. Holly, Manivannan Subramaniyan, Charles R. Gerfen, Marc V. Fuccillo
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36795-4
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author Kyuhyun Choi
Eugenio Piasini
Edgar Díaz-Hernández
Luigim Vargas Cifuentes
Nathan T. Henderson
Elizabeth N. Holly
Manivannan Subramaniyan
Charles R. Gerfen
Marc V. Fuccillo
author_facet Kyuhyun Choi
Eugenio Piasini
Edgar Díaz-Hernández
Luigim Vargas Cifuentes
Nathan T. Henderson
Elizabeth N. Holly
Manivannan Subramaniyan
Charles R. Gerfen
Marc V. Fuccillo
author_sort Kyuhyun Choi
collection DOAJ
description The prelimbic region of the prefrontal cortex is involved in goal-directed action. Here the authors investigate the function of the prelimbic pathways projecting along the anterior posterior striatal axis in value based decision making in male mice.
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spelling doaj.art-e5b6bbe1ca9a40469d4e131d7e6ad87c2023-04-09T11:20:49ZengNature PortfolioNature Communications2041-17232023-04-0114111910.1038/s41467-023-36795-4Distributed processing for value-based choice by prelimbic circuits targeting anterior-posterior dorsal striatal subregions in male miceKyuhyun Choi0Eugenio Piasini1Edgar Díaz-Hernández2Luigim Vargas Cifuentes3Nathan T. Henderson4Elizabeth N. Holly5Manivannan Subramaniyan6Charles R. Gerfen7Marc V. Fuccillo8Department of Neuroscience, Perelman School of Medicine, University of PennsylvaniaComputational Neuroscience Initiative, University of PennsylvaniaDepartment of Neuroscience, Perelman School of Medicine, University of PennsylvaniaDepartment of Neuroscience, Perelman School of Medicine, University of PennsylvaniaDepartment of Neuroscience, Perelman School of Medicine, University of PennsylvaniaDepartment of Neuroscience, Perelman School of Medicine, University of PennsylvaniaDepartment of Neuroscience, Perelman School of Medicine, University of PennsylvaniaLaboratory of Systems Neuroscience, National Institute of Mental Health (NIMH)Department of Neuroscience, Perelman School of Medicine, University of PennsylvaniaThe prelimbic region of the prefrontal cortex is involved in goal-directed action. Here the authors investigate the function of the prelimbic pathways projecting along the anterior posterior striatal axis in value based decision making in male mice.https://doi.org/10.1038/s41467-023-36795-4
spellingShingle Kyuhyun Choi
Eugenio Piasini
Edgar Díaz-Hernández
Luigim Vargas Cifuentes
Nathan T. Henderson
Elizabeth N. Holly
Manivannan Subramaniyan
Charles R. Gerfen
Marc V. Fuccillo
Distributed processing for value-based choice by prelimbic circuits targeting anterior-posterior dorsal striatal subregions in male mice
Nature Communications
title Distributed processing for value-based choice by prelimbic circuits targeting anterior-posterior dorsal striatal subregions in male mice
title_full Distributed processing for value-based choice by prelimbic circuits targeting anterior-posterior dorsal striatal subregions in male mice
title_fullStr Distributed processing for value-based choice by prelimbic circuits targeting anterior-posterior dorsal striatal subregions in male mice
title_full_unstemmed Distributed processing for value-based choice by prelimbic circuits targeting anterior-posterior dorsal striatal subregions in male mice
title_short Distributed processing for value-based choice by prelimbic circuits targeting anterior-posterior dorsal striatal subregions in male mice
title_sort distributed processing for value based choice by prelimbic circuits targeting anterior posterior dorsal striatal subregions in male mice
url https://doi.org/10.1038/s41467-023-36795-4
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