Involvement of nitric oxide in the effect of caffeine on the pentylenetetrazole-induced seizure threshold in mice
Background: Effect of caffeine on seizure is controversial in animal models of epilepsy. Caffeine is non-selective antagonist of A1 and A2A adenosine receptors. Meanwhile, nitric oxide-soluble guanylate cyclase-cyclic guanosine monophosphate (NO-sGC-cGMP) pathway is partly involved in the central...
| Main Authors: | , |
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| Format: | Article |
| Language: | fas |
| Published: |
Qazvin University of Medical Sciences & Health Services
2018-12-01
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| Series: | The Journal of Qazvin University of Medical Sciences |
| Subjects: | |
| Online Access: | http://journal.qums.ac.ir/browse.php?a_id=2728&sid=1&slc_lang=en |