Development of a Gold Nanoparticle Vaccine against Enterohemorrhagic <named-content content-type="genus-species">Escherichia coli</named-content> O157:H7

Development of a Gold Nanoparticle Vaccine against Enterohemorrhagic <named-content content-type="genus-species">Escherichia coli</named-content> O157:H7

ABSTRACT Here we exploit the natural properties of a synthetic nanoparticle (NP) scaffold as a subunit vaccine against enterohemorrhagic Escherichia coli (EHEC). Two EHEC-specific immunogenic antigens, namely, LomW and EscC, either alone or in combination, were covalently linked on the surface of go...

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Bibliographic Details
Main Authors: Javier I. Sanchez-Villamil, Daniel Tapia, Alfredo G. Torres
Format: Article
Language:English
Published: American Society for Microbiology 2019-08-01
Series:mBio
Subjects:
Escherichia coli
O157:H7
diarrhea
nanovaccines
pathogenic Escherichia
vaccines
Online Access:https://journals.asm.org/doi/10.1128/mBio.01869-19

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