A rare case of blood stream infection caused by yeast-Rhodotorula glutinis
Objective To report a rare severe case of blood stream infection by Rhodotorula glutinis(R.glutinis)and to share our experience in the diagnosis and treatment with colleagues. Methods The report described a case of catheter-associated R.glutinis bloodstream infection was analyzed after cardia...
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| Format: | Article |
| Language: | zho |
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Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2021-11-01
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| Series: | Jichu yixue yu linchuang |
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| Online Access: | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a210064.pdf |
| _version_ | 1797365752567693312 |
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| author | FENG Xiao-kai, HE Huai-wu, ZHANG Jia-hui, CHENG Wei, LONG Yun, GUO Fu-ping |
| author_facet | FENG Xiao-kai, HE Huai-wu, ZHANG Jia-hui, CHENG Wei, LONG Yun, GUO Fu-ping |
| author_sort | FENG Xiao-kai, HE Huai-wu, ZHANG Jia-hui, CHENG Wei, LONG Yun, GUO Fu-ping |
| collection | DOAJ |
| description | Objective To report a rare severe case of blood stream infection by Rhodotorula glutinis(R.glutinis)and to share our experience in the diagnosis and treatment with colleagues. Methods The report described a case of catheter-associated R.glutinis bloodstream infection was analyzed after cardiac surgery and reviewed relevant literature. Results R.glutinis bloodstream infection is uncommon in the world. It is difficult to make early diagnosis or tend to leading mis-diagnosis. This kind infection is inclined to occur in immuno-compromised individuals, and its clinical features are repeated high fever, failure of treatment with broad-spectrum antibiotics, normal G test (fungal D-glucose Sugar) results. The diagnosis depends on pathogen culture. R. glutinis is resistant to caspofungin and fluconazole but is sensitive to other antifungal drugs, such as amphotericin B, itraconazole and voriconazole. Patient responded well to intravenous amphotericin B and continued oral posaconazole antifungal therapy. Conclusions For critically ill patients who are not respond to broad-spectrum antibiotics and empirical antifungal (caspofungin and fluconazole) treatment, doctors should be aware of the possibility of bloodstream infection caused by yeast-R.glutinis, and treat patient with sensitive antifungal drugs and timely and avoid potential misdiagnosis. |
| first_indexed | 2024-03-08T16:54:24Z |
| format | Article |
| id | doaj.art-e5ba2ff1920b4a0485c6ba731a3f31c7 |
| institution | Directory Open Access Journal |
| issn | 1001-6325 |
| language | zho |
| last_indexed | 2024-03-08T16:54:24Z |
| publishDate | 2021-11-01 |
| publisher | Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. |
| record_format | Article |
| series | Jichu yixue yu linchuang |
| spelling | doaj.art-e5ba2ff1920b4a0485c6ba731a3f31c72024-01-05T03:07:24ZzhoInstitute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.Jichu yixue yu linchuang1001-63252021-11-01411116581661A rare case of blood stream infection caused by yeast-Rhodotorula glutinisFENG Xiao-kai, HE Huai-wu, ZHANG Jia-hui, CHENG Wei, LONG Yun, GUO Fu-ping01. Department of Intensive Care Unit; 3. Department of Infections Disease, Peking Union Medical College Hospital, CAMS & PUMC,Beijing 100730; 2. Department of Emergency, the People's Hospital of Hebi, Hebi 458030,ChinaObjective To report a rare severe case of blood stream infection by Rhodotorula glutinis(R.glutinis)and to share our experience in the diagnosis and treatment with colleagues. Methods The report described a case of catheter-associated R.glutinis bloodstream infection was analyzed after cardiac surgery and reviewed relevant literature. Results R.glutinis bloodstream infection is uncommon in the world. It is difficult to make early diagnosis or tend to leading mis-diagnosis. This kind infection is inclined to occur in immuno-compromised individuals, and its clinical features are repeated high fever, failure of treatment with broad-spectrum antibiotics, normal G test (fungal D-glucose Sugar) results. The diagnosis depends on pathogen culture. R. glutinis is resistant to caspofungin and fluconazole but is sensitive to other antifungal drugs, such as amphotericin B, itraconazole and voriconazole. Patient responded well to intravenous amphotericin B and continued oral posaconazole antifungal therapy. Conclusions For critically ill patients who are not respond to broad-spectrum antibiotics and empirical antifungal (caspofungin and fluconazole) treatment, doctors should be aware of the possibility of bloodstream infection caused by yeast-R.glutinis, and treat patient with sensitive antifungal drugs and timely and avoid potential misdiagnosis.http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a210064.pdfrhodotorula glutinis|bloodstream infection|candidemia |
| spellingShingle | FENG Xiao-kai, HE Huai-wu, ZHANG Jia-hui, CHENG Wei, LONG Yun, GUO Fu-ping A rare case of blood stream infection caused by yeast-Rhodotorula glutinis Jichu yixue yu linchuang rhodotorula glutinis|bloodstream infection|candidemia |
| title | A rare case of blood stream infection caused by yeast-Rhodotorula glutinis |
| title_full | A rare case of blood stream infection caused by yeast-Rhodotorula glutinis |
| title_fullStr | A rare case of blood stream infection caused by yeast-Rhodotorula glutinis |
| title_full_unstemmed | A rare case of blood stream infection caused by yeast-Rhodotorula glutinis |
| title_short | A rare case of blood stream infection caused by yeast-Rhodotorula glutinis |
| title_sort | rare case of blood stream infection caused by yeast rhodotorula glutinis |
| topic | rhodotorula glutinis|bloodstream infection|candidemia |
| url | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a210064.pdf |
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