Investigating of microsatellites instability in patients with hereditary non-polyposis colorectal cancer in Isfahan

Investigating of microsatellites instability in patients with hereditary non-polyposis colorectal cancer in Isfahan

Background: Microsatellites or simple sequence repeats are repeating sequences of deoxyribonucleic acid (DNA). Mutation in mismatch repair (MMR) genes can cause microsatellites instability (MSI) in some tumors. In familial disorder of hereditary non-polyposis colorectal cancer (HNPCC), there is a de...

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Bibliographic Details
Main Authors: Vida Homayouni, Mansour Salehi, Mohammad Kazemi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Advanced Biomedical Research
Subjects:
Hereditary non-polyposis colorectal cancer
microsatellites instability
MSH2
mismatch repair
Online Access:http://www.advbiores.net/article.asp?issn=2277-9175;year=2014;volume=3;issue=1;spage=145;epage=145;aulast=Homayouni

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