Antiarrhythmic drug therapy after atrial fibrillation ablation: data of the ESC-EHRA registry
Aim. Catheter ablation (CA) is an effective approach for rhythm control in atrial fibrillation (AF), however antiarrhythmic therapy (AAT) remains important. There is a lack of data about long-term AAT use after CA. This study evaluates AAT after CA for AF.Material and methods. In 2012-2016, EURObser...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
«FIRMA «SILICEA» LLC
2020-06-01
|
| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/3874 |
| _version_ | 1826561145103712256 |
|---|---|
| author | L. E. Korobchenko S. A. Bayramova V. E. Kharats O. N. Kachalkova A. Yu. Dmitriev R. E. Batalov D. P. Morgunov I. A. Silin A. A. Aleksandrovskiy D. V. Kryzhanovskiy A. B. Romanov E. A. Pokushalov D. S. Lebedev V. A. Kuznetsov G. V. Kolunin D. A. Zamanov S. Yu. Chetverikov S. M. Yashin S. V. Popov E. A. Ivanitsky A. I. Gorkov S. E. Mamchur V. A. Bazaev E. N. Mikhaylov |
| author_facet | L. E. Korobchenko S. A. Bayramova V. E. Kharats O. N. Kachalkova A. Yu. Dmitriev R. E. Batalov D. P. Morgunov I. A. Silin A. A. Aleksandrovskiy D. V. Kryzhanovskiy A. B. Romanov E. A. Pokushalov D. S. Lebedev V. A. Kuznetsov G. V. Kolunin D. A. Zamanov S. Yu. Chetverikov S. M. Yashin S. V. Popov E. A. Ivanitsky A. I. Gorkov S. E. Mamchur V. A. Bazaev E. N. Mikhaylov |
| author_sort | L. E. Korobchenko |
| collection | DOAJ |
| description | Aim. Catheter ablation (CA) is an effective approach for rhythm control in atrial fibrillation (AF), however antiarrhythmic therapy (AAT) remains important. There is a lack of data about long-term AAT use after CA. This study evaluates AAT after CA for AF.Material and methods. In 2012-2016, EURObservational Research Programme of Atrial Fibrillation Ablation Long-Term (EORP AFA L-T) registry was conducted, which included 476 Russian patients (57,1% — men; mean age — 57,1±8,7 years). The follow-up after CA was 12 months (available in 81,9% of patients). The use of AAT was evaluated prior to hospitalization, during hospitalization for CA, as well as at 3, 6 and 12 months of follow-up.Results. Prior to CA, 439 (92,2%) patients received AAT During CA, 459 (96,4%) patients were treated with AAT. After CA, AAT was used by 463 (97,3%), 370 (94,8%), and 307 (78,7%) patients at 3, 6 and 12 months of follow-up, respectively. There was no arrhythmia recurrence in 187 (47,9%) subjects. Among these patients, 40 (21,4%) received class IC or III AAT. The peak of AAT use was found for class IC agents within 3 months after CA (P<0,05), while for other drugs this trend was not observed. There were no factors associated with AAT usage in patients without arrhythmia recurrence after CA. A positive correlation of arrhythmia non-recurrence with a minimum number of previously used antiarrhythmic agents was revealed (RR=0,85; 95% CI 0,73-0,98; P=0,03).Conclusion. The frequency of AAT use after AF ablation is significantly reduced. However, there is a cohort of patients without documented arrhythmia recurrence still receiving AAT, which requires special attention of physicians. There were no clinical predictors of continued AAT in subjects without arrhythmia recurrence. |
| first_indexed | 2024-04-09T20:46:09Z |
| format | Article |
| id | doaj.art-e5bd9640955f4cf0916dd32d5a5e90f1 |
| institution | Directory Open Access Journal |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| last_indexed | 2025-03-14T09:27:31Z |
| publishDate | 2020-06-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj.art-e5bd9640955f4cf0916dd32d5a5e90f12025-03-02T11:42:51Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202020-06-0125510.15829/1560-4071-2020-38742930Antiarrhythmic drug therapy after atrial fibrillation ablation: data of the ESC-EHRA registryL. E. Korobchenko0S. A. Bayramova1V. E. Kharats2O. N. Kachalkova3A. Yu. Dmitriev4R. E. Batalov5D. P. Morgunov6I. A. Silin7A. A. Aleksandrovskiy8D. V. Kryzhanovskiy9A. B. Romanov10E. A. Pokushalov11D. S. Lebedev12V. A. Kuznetsov13G. V. Kolunin14D. A. Zamanov15S. Yu. Chetverikov16S. M. Yashin17S. V. Popov18E. A. Ivanitsky19A. I. Gorkov20S. E. Mamchur21V. A. Bazaev22E. N. Mikhaylov23Almazov National Medical Research Center of the Ministry of HealthMeshalkin National Medical Research Center of the Ministry of HealthTyumen Cardiological Scientific Center — branch of the Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of SciencesTyumen Cardiological Scientific Center — branch of the Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of SciencesKraevaya Clinical HospitalCardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of SciencesKhMAO-Yugra District Cardiological Dispensary, Center of Diagnostics and Cardiovascular SurgeryKhMAO-Yugra District Cardiological Dispensary, Center of Diagnostics and Cardiovascular SurgeryOgarev State Medical UniversityCity Clinical Hospital № 26Meshalkin National Medical Research Center of the Ministry of HealthMeshalkin National Medical Research Center of the Ministry of HealthAlmazov National Medical Research Center of the Ministry of HealthTyumen Cardiological Scientific Center — branch of the Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of SciencesTyumen Cardiological Scientific Center — branch of the Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of SciencesKraevaya Clinical HospitalKhMAO-Yugra District Clinical HospitalPavlov First Saint-Petersburg State Medical University of the Ministry of HealthCardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of SciencesFederal Center of Cardiovascular SurgeryKhMAO-Yugra District Cardiological Dispensary, Center of Diagnostics and Cardiovascular SurgeryResearch Institute for Complex Issues of Cardiovascular DiseasesSamara State Medical UniversityAlmazov National Medical Research Center of the Ministry of HealthAim. Catheter ablation (CA) is an effective approach for rhythm control in atrial fibrillation (AF), however antiarrhythmic therapy (AAT) remains important. There is a lack of data about long-term AAT use after CA. This study evaluates AAT after CA for AF.Material and methods. In 2012-2016, EURObservational Research Programme of Atrial Fibrillation Ablation Long-Term (EORP AFA L-T) registry was conducted, which included 476 Russian patients (57,1% — men; mean age — 57,1±8,7 years). The follow-up after CA was 12 months (available in 81,9% of patients). The use of AAT was evaluated prior to hospitalization, during hospitalization for CA, as well as at 3, 6 and 12 months of follow-up.Results. Prior to CA, 439 (92,2%) patients received AAT During CA, 459 (96,4%) patients were treated with AAT. After CA, AAT was used by 463 (97,3%), 370 (94,8%), and 307 (78,7%) patients at 3, 6 and 12 months of follow-up, respectively. There was no arrhythmia recurrence in 187 (47,9%) subjects. Among these patients, 40 (21,4%) received class IC or III AAT. The peak of AAT use was found for class IC agents within 3 months after CA (P<0,05), while for other drugs this trend was not observed. There were no factors associated with AAT usage in patients without arrhythmia recurrence after CA. A positive correlation of arrhythmia non-recurrence with a minimum number of previously used antiarrhythmic agents was revealed (RR=0,85; 95% CI 0,73-0,98; P=0,03).Conclusion. The frequency of AAT use after AF ablation is significantly reduced. However, there is a cohort of patients without documented arrhythmia recurrence still receiving AAT, which requires special attention of physicians. There were no clinical predictors of continued AAT in subjects without arrhythmia recurrence.https://russjcardiol.elpub.ru/jour/article/view/3874atrial fibrillationantiarrhythmic therapyregistrycatheter ablation |
| spellingShingle | L. E. Korobchenko S. A. Bayramova V. E. Kharats O. N. Kachalkova A. Yu. Dmitriev R. E. Batalov D. P. Morgunov I. A. Silin A. A. Aleksandrovskiy D. V. Kryzhanovskiy A. B. Romanov E. A. Pokushalov D. S. Lebedev V. A. Kuznetsov G. V. Kolunin D. A. Zamanov S. Yu. Chetverikov S. M. Yashin S. V. Popov E. A. Ivanitsky A. I. Gorkov S. E. Mamchur V. A. Bazaev E. N. Mikhaylov Antiarrhythmic drug therapy after atrial fibrillation ablation: data of the ESC-EHRA registry Российский кардиологический журнал atrial fibrillation antiarrhythmic therapy registry catheter ablation |
| title | Antiarrhythmic drug therapy after atrial fibrillation ablation: data of the ESC-EHRA registry |
| title_full | Antiarrhythmic drug therapy after atrial fibrillation ablation: data of the ESC-EHRA registry |
| title_fullStr | Antiarrhythmic drug therapy after atrial fibrillation ablation: data of the ESC-EHRA registry |
| title_full_unstemmed | Antiarrhythmic drug therapy after atrial fibrillation ablation: data of the ESC-EHRA registry |
| title_short | Antiarrhythmic drug therapy after atrial fibrillation ablation: data of the ESC-EHRA registry |
| title_sort | antiarrhythmic drug therapy after atrial fibrillation ablation data of the esc ehra registry |
| topic | atrial fibrillation antiarrhythmic therapy registry catheter ablation |
| url | https://russjcardiol.elpub.ru/jour/article/view/3874 |
| work_keys_str_mv | AT lekorobchenko antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT sabayramova antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT vekharats antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT onkachalkova antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT ayudmitriev antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT rebatalov antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT dpmorgunov antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT iasilin antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT aaaleksandrovskiy antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT dvkryzhanovskiy antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT abromanov antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT eapokushalov antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT dslebedev antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT vakuznetsov antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT gvkolunin antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT dazamanov antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT syuchetverikov antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT smyashin antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT svpopov antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT eaivanitsky antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT aigorkov antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT semamchur antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT vabazaev antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry AT enmikhaylov antiarrhythmicdrugtherapyafteratrialfibrillationablationdataoftheescehraregistry |