The Role of Ceramide Synthases in the Pathogenicity of Cryptococcus neoformans

The Role of Ceramide Synthases in the Pathogenicity of Cryptococcus neoformans

Summary: Cryptococcus neoformans (C. neoformans) is estimated to cause about 220,000 new cases every year in patients with AIDS, despite advances in antifungal treatments. C. neoformans possesses a remarkable ability to disseminate through an immunocompromised host, making treatment difficult. Here,...

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Bibliographic Details
Main Authors: Mansa A. Munshi, Justin M. Gardin, Ashutosh Singh, Chiara Luberto, Robert Rieger, Tejas Bouklas, Bettina C. Fries, Maurizio Del Poeta
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Cell Reports
Subjects:
ceramide
ceramide synthase
sphingolipids
Cryptococcus neoformans
virulence
pathogenicity
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718300676

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