Flavonoid Phloretin Inhibits Adipogenesis and Increases OPG Expression in Adipocytes Derived from Human Bone-Marrow Mesenchymal Stromal-Cells

Flavonoid Phloretin Inhibits Adipogenesis and Increases OPG Expression in Adipocytes Derived from Human Bone-Marrow Mesenchymal Stromal-Cells

Phloretin (a flavonoid abundant in apple), has antioxidant, anti-inflammatory, and glucose-transporter inhibitory properties. Thus, it has interesting pharmacological and nutraceutical potential. Bone-marrow mesenchymal stem cells (MSC) have high differentiation capacity, being essential for maintai...

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Bibliographic Details
Main Authors: Antonio Casado-Díaz, Ángel Rodríguez-Ramos, Bárbara Torrecillas-Baena, Gabriel Dorado, José Manuel Quesada-Gómez, María Ángeles Gálvez-Moreno
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Nutrients
Subjects:
phloretin
human mesenchymal stem cells
adipogenesis
obesity
bone
Online Access:https://www.mdpi.com/2072-6643/13/11/4185

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