The Endoplasmic Reticulum Stress Sensor Inositol-Requiring Enzyme 1α Augments Bacterial Killing through Sustained Oxidant Production

The Endoplasmic Reticulum Stress Sensor Inositol-Requiring Enzyme 1α Augments Bacterial Killing through Sustained Oxidant Production

ABSTRACT Bacterial infection can trigger cellular stress programs, such as the unfolded protein response (UPR), which occurs when misfolded proteins accumulate within the endoplasmic reticulum (ER). Here, we used the human pathogen methicillin-resistant Staphylococcus aureus (MRSA) as an infection m...

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Bibliographic Details
Main Authors: Basel H. Abuaita, Kristin M. Burkholder, Blaise R. Boles, Mary X. O’Riordan
Format: Article
Language:English
Published: American Society for Microbiology 2015-09-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00705-15

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