Measles Outbreak in a Community with Very Low Vaccine Coverage, the Netherlands
A 1999-2000 measles epidemic in the Netherlands started with an outbreak in an orthodox reformed elementary school with 7% vaccine coverage. The overall attack rate was 37%: 213 clinical cases among the 255 participating pupils (response 62%) and 327 household members. The attack rate ranged from 0%...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Centers for Disease Control and Prevention
2001-06-01
|
| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/7/7/01-7743_article |
| _version_ | 1818556041989718016 |
|---|---|
| author | Susan van den Hof Christine M.A. Meffre Marina A.E. Conyn-van Spaendonck Frits Woonink Hester E. de Melker Rob S. van Binnendijk |
| author_facet | Susan van den Hof Christine M.A. Meffre Marina A.E. Conyn-van Spaendonck Frits Woonink Hester E. de Melker Rob S. van Binnendijk |
| author_sort | Susan van den Hof |
| collection | DOAJ |
| description | A 1999-2000 measles epidemic in the Netherlands started with an outbreak in an orthodox reformed elementary school with 7% vaccine coverage. The overall attack rate was 37%: 213 clinical cases among the 255 participating pupils (response 62%) and 327 household members. The attack rate ranged from 0% for the oldest groups of pupils to 88% for the youngest, who had not been exposed in previous measles epidemics. None of 25 vaccinated pupils had clinical symptoms. Among pupils with clinical symptoms, the self-reported complication rate was 25%. These data confirm that measles infection causes severe disease and that vaccination is the most effective means of preventing the disease and its complications. The data also show that clusters of persons refraining from vaccination interfere with measles elimination even in populations with very high overall vaccine coverage (96%). |
| first_indexed | 2024-12-13T23:42:21Z |
| format | Article |
| id | doaj.art-e5c839a32ac546b390e73435dff055f9 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-13T23:42:21Z |
| publishDate | 2001-06-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-e5c839a32ac546b390e73435dff055f92022-12-21T23:27:08ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592001-06-017759359710.3201/eid0707.017743Measles Outbreak in a Community with Very Low Vaccine Coverage, the NetherlandsSusan van den HofChristine M.A. MeffreMarina A.E. Conyn-van SpaendonckFrits WooninkHester E. de MelkerRob S. van BinnendijkA 1999-2000 measles epidemic in the Netherlands started with an outbreak in an orthodox reformed elementary school with 7% vaccine coverage. The overall attack rate was 37%: 213 clinical cases among the 255 participating pupils (response 62%) and 327 household members. The attack rate ranged from 0% for the oldest groups of pupils to 88% for the youngest, who had not been exposed in previous measles epidemics. None of 25 vaccinated pupils had clinical symptoms. Among pupils with clinical symptoms, the self-reported complication rate was 25%. These data confirm that measles infection causes severe disease and that vaccination is the most effective means of preventing the disease and its complications. The data also show that clusters of persons refraining from vaccination interfere with measles elimination even in populations with very high overall vaccine coverage (96%).https://wwwnc.cdc.gov/eid/article/7/7/01-7743_articlemeaslesoutbreakvaccinationeliminationthe Netherlands |
| spellingShingle | Susan van den Hof Christine M.A. Meffre Marina A.E. Conyn-van Spaendonck Frits Woonink Hester E. de Melker Rob S. van Binnendijk Measles Outbreak in a Community with Very Low Vaccine Coverage, the Netherlands Emerging Infectious Diseases measles outbreak vaccination elimination the Netherlands |
| title | Measles Outbreak in a Community with Very Low Vaccine Coverage, the Netherlands |
| title_full | Measles Outbreak in a Community with Very Low Vaccine Coverage, the Netherlands |
| title_fullStr | Measles Outbreak in a Community with Very Low Vaccine Coverage, the Netherlands |
| title_full_unstemmed | Measles Outbreak in a Community with Very Low Vaccine Coverage, the Netherlands |
| title_short | Measles Outbreak in a Community with Very Low Vaccine Coverage, the Netherlands |
| title_sort | measles outbreak in a community with very low vaccine coverage the netherlands |
| topic | measles outbreak vaccination elimination the Netherlands |
| url | https://wwwnc.cdc.gov/eid/article/7/7/01-7743_article |
| work_keys_str_mv | AT susanvandenhof measlesoutbreakinacommunitywithverylowvaccinecoveragethenetherlands AT christinemameffre measlesoutbreakinacommunitywithverylowvaccinecoveragethenetherlands AT marinaaeconynvanspaendonck measlesoutbreakinacommunitywithverylowvaccinecoveragethenetherlands AT fritswoonink measlesoutbreakinacommunitywithverylowvaccinecoveragethenetherlands AT hesteredemelker measlesoutbreakinacommunitywithverylowvaccinecoveragethenetherlands AT robsvanbinnendijk measlesoutbreakinacommunitywithverylowvaccinecoveragethenetherlands |