2D QSAR, design, docking study and ADMET of some N-aryl derivatives concerning inhibitory activity against Alzheimer disease

2D QSAR, design, docking study and ADMET of some N-aryl derivatives concerning inhibitory activity against Alzheimer disease

Abstract Background Alzheimer disease (AD) is an ailment that disturbs mainly people of old age. The fundamental remedial way to deal with AD depends on the utilization of AChEI. The design of new intense and particular AChEI is critical in drug discovery. In silico technique will be used to solve t...

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Bibliographic Details
Main Authors: Abduljelil Ajala, Adamu Uzairu, Gideon A. Shallangwa, Stephen E. Abechi
Format: Article
Language:English
Published: SpringerOpen 2022-06-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
QSAR
Molecular docking
Design
Alzheimer disease
AChEI
Online Access:https://doi.org/10.1186/s43094-022-00420-w

Internet

https://doi.org/10.1186/s43094-022-00420-w

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