Arabinosyltransferase C Mediates Multiple Drugs Intrinsic Resistance by Altering Cell Envelope Permeability in Mycobacterium abscessus

Arabinosyltransferase C Mediates Multiple Drugs Intrinsic Resistance by Altering Cell Envelope Permeability in Mycobacterium abscessus

ABSTRACT Mycobacterium abscessus is an emerging human pathogen leading to significant morbidity and even mortality, intrinsically resistant to almost all the antibiotics available and so can be a nightmare. Mechanisms of its intrinsic resistance remain not fully understood. Here, we selected and con...

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Main Authors: Shuai Wang, Xiaoyin Cai, Wei Yu, Sheng Zeng, Jingran Zhang, Lingmin Guo, Yamin Gao, Zhili Lu, H. M. Adnan Hameed, Cuiting Fang, Xirong Tian, Buhari Yusuf, Chiranjibi Chhotaray, M. D. Shah Alam, Buchang Zhang, Honghua Ge, Dmitry A. Maslov, Gregory M. Cook, Jiacong Peng, Yongping Lin, Nanshan Zhong, Guoliang Zhang, Tianyu Zhang
Format: Article
Language:English
Published: American Society for Microbiology 2022-08-01
Series:Microbiology Spectrum
Subjects:
Mycobacterium abscessus
intrinsic resistance
MAB_0189c
permeability
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02763-21

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