Epigenetic therapy in lung cancer – role of microRNAs
Lung cancer is the leading cause of cancer deaths worldwide. microRNAs are a class of small non-coding RNA species that have been implicated in the control of many fundamental cellular and physiological processes such as cellular differentiation, proliferation, apoptosis and stem cell maintenance. S...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2013-06-01
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| Series: | Frontiers in Oncology |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00158/full |
| Summary: | Lung cancer is the leading cause of cancer deaths worldwide. microRNAs are a class of small non-coding RNA species that have been implicated in the control of many fundamental cellular and physiological processes such as cellular differentiation, proliferation, apoptosis and stem cell maintenance. Some microRNAs have been categorized as oncomiRs as opposed to tumor suppressor miRs This review focuses on the role of miRNAs in the lung cancer carcinogenesis and their potential as diagnostic, prognostic or predictive markers. |
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| ISSN: | 2234-943X |