Epigenetic therapy in lung cancer – role of microRNAs

Lung cancer is the leading cause of cancer deaths worldwide. microRNAs are a class of small non-coding RNA species that have been implicated in the control of many fundamental cellular and physiological processes such as cellular differentiation, proliferation, apoptosis and stem cell maintenance. S...

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Main Author: Sacha I Rothschild
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-06-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00158/full
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author Sacha I Rothschild
author_facet Sacha I Rothschild
author_sort Sacha I Rothschild
collection DOAJ
description Lung cancer is the leading cause of cancer deaths worldwide. microRNAs are a class of small non-coding RNA species that have been implicated in the control of many fundamental cellular and physiological processes such as cellular differentiation, proliferation, apoptosis and stem cell maintenance. Some microRNAs have been categorized as oncomiRs as opposed to tumor suppressor miRs This review focuses on the role of miRNAs in the lung cancer carcinogenesis and their potential as diagnostic, prognostic or predictive markers.
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spelling doaj.art-e5cfb5d44600433b9290f25d9c985b452022-12-22T03:19:54ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2013-06-01310.3389/fonc.2013.0015853990Epigenetic therapy in lung cancer – role of microRNAsSacha I Rothschild0University Hospital BaselLung cancer is the leading cause of cancer deaths worldwide. microRNAs are a class of small non-coding RNA species that have been implicated in the control of many fundamental cellular and physiological processes such as cellular differentiation, proliferation, apoptosis and stem cell maintenance. Some microRNAs have been categorized as oncomiRs as opposed to tumor suppressor miRs This review focuses on the role of miRNAs in the lung cancer carcinogenesis and their potential as diagnostic, prognostic or predictive markers.http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00158/fullmicroRNAmiRNAtherapybiomarkerlung cancerdiagnosis
spellingShingle Sacha I Rothschild
Epigenetic therapy in lung cancer – role of microRNAs
Frontiers in Oncology
microRNA
miRNA
therapy
biomarker
lung cancer
diagnosis
title Epigenetic therapy in lung cancer – role of microRNAs
title_full Epigenetic therapy in lung cancer – role of microRNAs
title_fullStr Epigenetic therapy in lung cancer – role of microRNAs
title_full_unstemmed Epigenetic therapy in lung cancer – role of microRNAs
title_short Epigenetic therapy in lung cancer – role of microRNAs
title_sort epigenetic therapy in lung cancer role of micrornas
topic microRNA
miRNA
therapy
biomarker
lung cancer
diagnosis
url http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00158/full
work_keys_str_mv AT sachairothschild epigenetictherapyinlungcancerroleofmicrornas