Clinical, economic, and health‐related quality of life outcomes in patients with overweight or obesity in the United States: 2016–2018
Abstract Objectives This study aimed to estimate clinical, economic (including productivity), and health‐related quality of life (HRQoL) outcomes and associated individual characteristics among adults with overweight (OW) or obesity in the United States. Methods This study included adult respondents...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2024-02-01
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| Series: | Obesity Science & Practice |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/osp4.726 |
| _version_ | 1797294368336379904 |
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| author | Joanna P. MacEwan Kevin Chiu Nadia N. Ahmad Naomi Sacks Shraddha Shinde Jiat Ling Poon Hong Kan |
| author_facet | Joanna P. MacEwan Kevin Chiu Nadia N. Ahmad Naomi Sacks Shraddha Shinde Jiat Ling Poon Hong Kan |
| author_sort | Joanna P. MacEwan |
| collection | DOAJ |
| description | Abstract Objectives This study aimed to estimate clinical, economic (including productivity), and health‐related quality of life (HRQoL) outcomes and associated individual characteristics among adults with overweight (OW) or obesity in the United States. Methods This study included adult respondents with body mass index (BMI) ≥18.5 kg/m2 in the 2017–2018 National Health and Nutrition Examination Survey (NHANES) and 2016 Medical Expenditure Panel Survey. Respondents were classified according to BMI. Individual characteristics were described by BMI categories. Multivariable regression models estimated the association between BMI categories and outcomes, adjusting for individual characteristics. Results Nearly three‐quarters (73.7%) of NHANES participants were OW or obese. Relative to Normal weight (NW), respondents with Class 3 obesity had more obesity‐related complications (2.07 vs. 4.62, p < 0.001). Higher BMI was associated with significantly lower HRQoL, lower productivity, and higher healthcare expenditures as well as more frequent weight loss attempts in the previous 12 months. Weight loss surgery and prescription anti‐obesity medications (AOMs) were used only by a very small proportion of individuals. Despite frequent weight loss attempts, most respondents did not achieve clinically meaningful weight loss. Conclusions Adults with OW or obesity experienced worse clinical, economic and HRQoL outcomes than those with NW. Better use of evidence‐based obesity treatments, including prescription AOMs, should be considered to achieve more clinically meaningful weight reduction and improved outcomes in individuals with OW or obesity. |
| first_indexed | 2024-03-07T21:29:13Z |
| format | Article |
| id | doaj.art-e5d08d9abbc34f42a0459564a343a2f9 |
| institution | Directory Open Access Journal |
| issn | 2055-2238 |
| language | English |
| last_indexed | 2024-03-07T21:29:13Z |
| publishDate | 2024-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | Obesity Science & Practice |
| spelling | doaj.art-e5d08d9abbc34f42a0459564a343a2f92024-02-27T03:30:31ZengWileyObesity Science & Practice2055-22382024-02-01101n/an/a10.1002/osp4.726Clinical, economic, and health‐related quality of life outcomes in patients with overweight or obesity in the United States: 2016–2018Joanna P. MacEwan0Kevin Chiu1Nadia N. Ahmad2Naomi Sacks3Shraddha Shinde4Jiat Ling Poon5Hong Kan6Genesis Research Group Hoboken New Jersey USASanta Clara University Santa Clara California USAEli Lilly & Company Indianapolis Indiana USAHEORStrategies Boston Massachusetts USAEli Lilly & Company Indianapolis Indiana USAEli Lilly & Company Indianapolis Indiana USAEli Lilly & Company Indianapolis Indiana USAAbstract Objectives This study aimed to estimate clinical, economic (including productivity), and health‐related quality of life (HRQoL) outcomes and associated individual characteristics among adults with overweight (OW) or obesity in the United States. Methods This study included adult respondents with body mass index (BMI) ≥18.5 kg/m2 in the 2017–2018 National Health and Nutrition Examination Survey (NHANES) and 2016 Medical Expenditure Panel Survey. Respondents were classified according to BMI. Individual characteristics were described by BMI categories. Multivariable regression models estimated the association between BMI categories and outcomes, adjusting for individual characteristics. Results Nearly three‐quarters (73.7%) of NHANES participants were OW or obese. Relative to Normal weight (NW), respondents with Class 3 obesity had more obesity‐related complications (2.07 vs. 4.62, p < 0.001). Higher BMI was associated with significantly lower HRQoL, lower productivity, and higher healthcare expenditures as well as more frequent weight loss attempts in the previous 12 months. Weight loss surgery and prescription anti‐obesity medications (AOMs) were used only by a very small proportion of individuals. Despite frequent weight loss attempts, most respondents did not achieve clinically meaningful weight loss. Conclusions Adults with OW or obesity experienced worse clinical, economic and HRQoL outcomes than those with NW. Better use of evidence‐based obesity treatments, including prescription AOMs, should be considered to achieve more clinically meaningful weight reduction and improved outcomes in individuals with OW or obesity.https://doi.org/10.1002/osp4.726HRQoLobesityoutcomesoverweight |
| spellingShingle | Joanna P. MacEwan Kevin Chiu Nadia N. Ahmad Naomi Sacks Shraddha Shinde Jiat Ling Poon Hong Kan Clinical, economic, and health‐related quality of life outcomes in patients with overweight or obesity in the United States: 2016–2018 Obesity Science & Practice HRQoL obesity outcomes overweight |
| title | Clinical, economic, and health‐related quality of life outcomes in patients with overweight or obesity in the United States: 2016–2018 |
| title_full | Clinical, economic, and health‐related quality of life outcomes in patients with overweight or obesity in the United States: 2016–2018 |
| title_fullStr | Clinical, economic, and health‐related quality of life outcomes in patients with overweight or obesity in the United States: 2016–2018 |
| title_full_unstemmed | Clinical, economic, and health‐related quality of life outcomes in patients with overweight or obesity in the United States: 2016–2018 |
| title_short | Clinical, economic, and health‐related quality of life outcomes in patients with overweight or obesity in the United States: 2016–2018 |
| title_sort | clinical economic and health related quality of life outcomes in patients with overweight or obesity in the united states 2016 2018 |
| topic | HRQoL obesity outcomes overweight |
| url | https://doi.org/10.1002/osp4.726 |
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