Molecular epidemiology of Crimean-Congo hemorrhagic fever virus genome isolated from ticks of Hamadan province of Iran
Background & objectives: Crimean-Congo hemorrhagic fever (CCHF) virus is a tick-borne memberof the genus Nairovirus, family Bunyaviridae. CCHFV has been isolated from at least 31 differenttick species. The virus is transmitted through the bite of an infected tick, or by direct contact withCCHFV-...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2010-12-01
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| Series: | Journal of Vector Borne Diseases |
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| Online Access: | http://www.mrcindia.org/journal/issues/474211.pdf |
| _version_ | 1811221186996076544 |
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| author | F. Tahmasebi , S.M. Ghiasi , E. Mostafavi , M. Moradi , N. Piazak , A. Mozafari , A. Haeri , A.R. Fooks , S. Chinikar |
| author_facet | F. Tahmasebi , S.M. Ghiasi , E. Mostafavi , M. Moradi , N. Piazak , A. Mozafari , A. Haeri , A.R. Fooks , S. Chinikar |
| author_sort | F. Tahmasebi , S.M. Ghiasi , E. Mostafavi , M. Moradi , N. Piazak , A. Mozafari , A. Haeri , A.R. Fooks , S. Chinikar |
| collection | DOAJ |
| description | Background & objectives: Crimean-Congo hemorrhagic fever (CCHF) virus is a tick-borne memberof the genus Nairovirus, family Bunyaviridae. CCHFV has been isolated from at least 31 differenttick species. The virus is transmitted through the bite of an infected tick, or by direct contact withCCHFV-infected patients or the products of infected livestock. This study was undertaken to studythe genetic relationship and distribution of CCHFV in the tick population of Hamadan province ofIran.Method: In this study, RT-PCR has been used for detection of the CCHFV genome.Results: This genome was detected in 19.2% of the ticks collected from livestock of differentregions of the Hamadan province in western Iran. The infected species belonged to Hyalommadetritum, H. anatolicum, Rhipicephalus sanguineus and Argas reflexus. With one exception, geneticanalysis of the virus genome isolates showed high sequence identity to each other. Even thoughthey clustered in the same group with the strain circulating in Iran, they had a closer relationshipto the Matin strain.Interpretation & conclusion: Vector control programs should be applied for reducing populationdensity of potential tick vectors in this province. Further surveys are indicated in this region toprovide a better view of the distribution and epidemiology of the virus. |
| first_indexed | 2024-04-12T07:54:59Z |
| format | Article |
| id | doaj.art-e5d2954884184aa09dfc7f403cd22538 |
| institution | Directory Open Access Journal |
| issn | 0972-9062 |
| language | English |
| last_indexed | 2024-04-12T07:54:59Z |
| publishDate | 2010-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Vector Borne Diseases |
| spelling | doaj.art-e5d2954884184aa09dfc7f403cd225382022-12-22T03:41:30ZengWolters Kluwer Medknow PublicationsJournal of Vector Borne Diseases0972-90622010-12-01474211216Molecular epidemiology of Crimean-Congo hemorrhagic fever virus genome isolated from ticks of Hamadan province of IranF. Tahmasebi , S.M. Ghiasi , E. Mostafavi , M. Moradi , N. Piazak , A. Mozafari , A. Haeri , A.R. Fooks , S. ChinikarBackground & objectives: Crimean-Congo hemorrhagic fever (CCHF) virus is a tick-borne memberof the genus Nairovirus, family Bunyaviridae. CCHFV has been isolated from at least 31 differenttick species. The virus is transmitted through the bite of an infected tick, or by direct contact withCCHFV-infected patients or the products of infected livestock. This study was undertaken to studythe genetic relationship and distribution of CCHFV in the tick population of Hamadan province ofIran.Method: In this study, RT-PCR has been used for detection of the CCHFV genome.Results: This genome was detected in 19.2% of the ticks collected from livestock of differentregions of the Hamadan province in western Iran. The infected species belonged to Hyalommadetritum, H. anatolicum, Rhipicephalus sanguineus and Argas reflexus. With one exception, geneticanalysis of the virus genome isolates showed high sequence identity to each other. Even thoughthey clustered in the same group with the strain circulating in Iran, they had a closer relationshipto the Matin strain.Interpretation & conclusion: Vector control programs should be applied for reducing populationdensity of potential tick vectors in this province. Further surveys are indicated in this region toprovide a better view of the distribution and epidemiology of the virus.http://www.mrcindia.org/journal/issues/474211.pdfArgas reflexusCCHFRT-PC |
| spellingShingle | F. Tahmasebi , S.M. Ghiasi , E. Mostafavi , M. Moradi , N. Piazak , A. Mozafari , A. Haeri , A.R. Fooks , S. Chinikar Molecular epidemiology of Crimean-Congo hemorrhagic fever virus genome isolated from ticks of Hamadan province of Iran Journal of Vector Borne Diseases Argas reflexus CCHF RT-PC |
| title | Molecular epidemiology of Crimean-Congo hemorrhagic fever virus genome isolated from ticks of Hamadan province of Iran |
| title_full | Molecular epidemiology of Crimean-Congo hemorrhagic fever virus genome isolated from ticks of Hamadan province of Iran |
| title_fullStr | Molecular epidemiology of Crimean-Congo hemorrhagic fever virus genome isolated from ticks of Hamadan province of Iran |
| title_full_unstemmed | Molecular epidemiology of Crimean-Congo hemorrhagic fever virus genome isolated from ticks of Hamadan province of Iran |
| title_short | Molecular epidemiology of Crimean-Congo hemorrhagic fever virus genome isolated from ticks of Hamadan province of Iran |
| title_sort | molecular epidemiology of crimean congo hemorrhagic fever virus genome isolated from ticks of hamadan province of iran |
| topic | Argas reflexus CCHF RT-PC |
| url | http://www.mrcindia.org/journal/issues/474211.pdf |
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