TRPV1 antagonist JNJ-39439335 (mavatrep) demonstrates proof of pharmacology in healthy men: a first-in-human, double-blind, placebo-controlled, randomized, sequential group study

Abstract. This double-blind, randomized, placebo-controlled, sequential group, phase 1 study was designed to assess in healthy men, the safety, tolerability, pharmacokinetics, and translational pharmacodynamics of JNJ-39439335 (mavatrep), a transient receptor potential vanilloid subtype 1 antagonist...

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Bibliographic Details
Main Authors: Prasarn Manitpisitkul, Michael Brandt, Christopher M. Flores, Velga Kenigs, John A. Moyer, Gary Romano, Kevin Shalayda, Arthur J. Mayorga
Format: Article
Language:English
Published: Wolters Kluwer 2016-10-01
Series:PAIN Reports
Online Access:http://journals.lww.com/painrpts/fulltext/10.1097/PR9.0000000000000576