Acute Kidney Injury in Nephrotic Syndrome
Nephrotic syndrome (NS) is one of the commonest kidney diseases seen in childhood and is characterized by a relapsing remitting course. Various complications have been reported in children with NS, including infections, thromboembolism, hypovolemia, and acute kidney injury (AKI). There is often a mo...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2019-01-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fped.2018.00428/full |
| _version_ | 1818388528853155840 |
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| author | Shina Menon |
| author_facet | Shina Menon |
| author_sort | Shina Menon |
| collection | DOAJ |
| description | Nephrotic syndrome (NS) is one of the commonest kidney diseases seen in childhood and is characterized by a relapsing remitting course. Various complications have been reported in children with NS, including infections, thromboembolism, hypovolemia, and acute kidney injury (AKI). There is often a modest decrease in renal function in patients with active proteinuria due to decreased glomerular permeability that improves when they go into remission. However, more pronounced AKI in NS is multifactorial in origin. It is most often secondary to hypovolemia, nephrotoxic medications, and infections, although other reasons may also be seen. Recent years have seen an increase in the incidence of AKI in NS. There is limited data on the correlation between AKI in pediatric NS and long-term outcomes. A better understanding of this increasingly common condition will help improve patient outcomes. |
| first_indexed | 2024-12-14T04:27:17Z |
| format | Article |
| id | doaj.art-e5d83713982e4a7c836c855ffb69ab1e |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-12-14T04:27:17Z |
| publishDate | 2019-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-e5d83713982e4a7c836c855ffb69ab1e2022-12-21T23:17:11ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602019-01-01610.3389/fped.2018.00428436034Acute Kidney Injury in Nephrotic SyndromeShina MenonNephrotic syndrome (NS) is one of the commonest kidney diseases seen in childhood and is characterized by a relapsing remitting course. Various complications have been reported in children with NS, including infections, thromboembolism, hypovolemia, and acute kidney injury (AKI). There is often a modest decrease in renal function in patients with active proteinuria due to decreased glomerular permeability that improves when they go into remission. However, more pronounced AKI in NS is multifactorial in origin. It is most often secondary to hypovolemia, nephrotoxic medications, and infections, although other reasons may also be seen. Recent years have seen an increase in the incidence of AKI in NS. There is limited data on the correlation between AKI in pediatric NS and long-term outcomes. A better understanding of this increasingly common condition will help improve patient outcomes.https://www.frontiersin.org/article/10.3389/fped.2018.00428/fullacute kidney injuryminimal change diseaserenal failureCKDnephrotic syndrome |
| spellingShingle | Shina Menon Acute Kidney Injury in Nephrotic Syndrome Frontiers in Pediatrics acute kidney injury minimal change disease renal failure CKD nephrotic syndrome |
| title | Acute Kidney Injury in Nephrotic Syndrome |
| title_full | Acute Kidney Injury in Nephrotic Syndrome |
| title_fullStr | Acute Kidney Injury in Nephrotic Syndrome |
| title_full_unstemmed | Acute Kidney Injury in Nephrotic Syndrome |
| title_short | Acute Kidney Injury in Nephrotic Syndrome |
| title_sort | acute kidney injury in nephrotic syndrome |
| topic | acute kidney injury minimal change disease renal failure CKD nephrotic syndrome |
| url | https://www.frontiersin.org/article/10.3389/fped.2018.00428/full |
| work_keys_str_mv | AT shinamenon acutekidneyinjuryinnephroticsyndrome |