A review on synthetic investigation for quinoline- recent green approaches
Quinolines are a prominent heterocyclic motif and crucial building blocks in creating physiologically active compounds. Due to the fast development of novel medicines with a quinoline nucleus, numerous research papers have been published in a short amount of time. Therefore, to comprehend the presen...
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Format: | Article |
Language: | English |
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Taylor & Francis Group
2022-04-01
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Series: | Green Chemistry Letters and Reviews |
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Online Access: | https://www.tandfonline.com/doi/10.1080/17518253.2022.2064194 |
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author | Ashish Patel Stuti Patel Meshwa Mehta Yug Patel Rushi Patel Drashti Shah Darshini Patel Umang Shah Mehul Patel Swayamprakash Patel Nilay Solanki Tushar Bambharoliya Sandip Patel Afzal Nagani Harnisha Patel Jitendra Vaghasiya Hirak Shah Bijal Prajapati Mrudangsinh Rathod Bhargav Bhimani Riddhisiddhi Patel Vashisth Bhavsar Brijesh Rakholiya Maitri Patel Prexa Patel |
author_facet | Ashish Patel Stuti Patel Meshwa Mehta Yug Patel Rushi Patel Drashti Shah Darshini Patel Umang Shah Mehul Patel Swayamprakash Patel Nilay Solanki Tushar Bambharoliya Sandip Patel Afzal Nagani Harnisha Patel Jitendra Vaghasiya Hirak Shah Bijal Prajapati Mrudangsinh Rathod Bhargav Bhimani Riddhisiddhi Patel Vashisth Bhavsar Brijesh Rakholiya Maitri Patel Prexa Patel |
author_sort | Ashish Patel |
collection | DOAJ |
description | Quinolines are a prominent heterocyclic motif and crucial building blocks in creating physiologically active compounds. Due to the fast development of novel medicines with a quinoline nucleus, numerous research papers have been published in a short amount of time. Therefore, to comprehend the present state of the quinoline nucleus in medicinal chemistry science, it is necessary to combine new information with older data. So far, several traditional synthesis techniques have been reported in the literature to synthesize this scaffold. Pfitzinger, Gould–Jacob, Friedlander, Skraup, Doebner–von Miller, and Conrad–Limpach are examples of old synthetic methods. However, they need expensive and demanding conditions, such as high temperature, the use of non-biodegradable chemical compounds degrade the ecosystem, create irritation or harm as pollutants, and represent a threat to the environment. However, traditional synthesis processes need a difficult and time-consuming apparatus set-up, resulting in high costs and pollutants. As a result, scientists are presently developing new and innovative techniques to decrease the use of chemicals, solvents, and catalysts, which are detrimental to both humans and the environment. Therefore, we have attempted to shed light in this current review on various reactions to produce quinolines and their derivatives using various green synthetic methods. |
first_indexed | 2024-12-12T07:21:47Z |
format | Article |
id | doaj.art-e5dafe7cc76b4a239c12d13a38a93277 |
institution | Directory Open Access Journal |
issn | 1751-8253 1751-7192 |
language | English |
last_indexed | 2024-12-12T07:21:47Z |
publishDate | 2022-04-01 |
publisher | Taylor & Francis Group |
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spelling | doaj.art-e5dafe7cc76b4a239c12d13a38a932772022-12-22T00:33:20ZengTaylor & Francis GroupGreen Chemistry Letters and Reviews1751-82531751-71922022-04-0115233737210.1080/17518253.2022.2064194A review on synthetic investigation for quinoline- recent green approachesAshish Patel0Stuti Patel1Meshwa Mehta2Yug Patel3Rushi Patel4Drashti Shah5Darshini Patel6Umang Shah7Mehul Patel8Swayamprakash Patel9Nilay Solanki10Tushar Bambharoliya11Sandip Patel12Afzal Nagani13Harnisha Patel14Jitendra Vaghasiya15Hirak Shah16Bijal Prajapati17Mrudangsinh Rathod18Bhargav Bhimani19Riddhisiddhi Patel20Vashisth Bhavsar21Brijesh Rakholiya22Maitri Patel23Prexa Patel24Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, CHARUSAT- Campus, Changa, Anand, India.Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, CHARUSAT- Campus, Changa, Anand, India.Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, CHARUSAT- Campus, Changa, Anand, India.Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, CHARUSAT- Campus, Changa, Anand, India.Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, CHARUSAT- Campus, Changa, Anand, India.Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, CHARUSAT- Campus, Changa, Anand, India.Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, CHARUSAT- Campus, Changa, Anand, India.Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, CHARUSAT- Campus, Changa, Anand, India.Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, CHARUSAT- Campus, Changa, Anand, India.Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, CHARUSAT- Campus, Changa, Anand, India.Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, CHARUSAT- Campus, Changa, Anand, India.North Carolina State University, North Carolina, USAL.M.College of Pharmacy, Department of Pharmacology, Ahmedabad, IndiaDepartment of Pharmaceutical Chemistry, Parul University, Vadodara, IndiaDepartment of Pharmaceutical Chemistry, Parul University, Vadodara, IndiaDepartment of Pharmaceutical Chemistry, Parul University, Vadodara, IndiaDepartment of Pharmaceutical Chemistry, Parul University, Vadodara, IndiaDepartment of Pharmaceutical Chemistry, Parul University, Vadodara, IndiaDepartment of Pharmaceutical Chemistry, Parul University, Vadodara, IndiaPiramal Pharma Limited, Pharmaceutical Special Economic Zone, Ahmedabad, IndiaDepartment of Pharmaceutical Sciences, Saurashtra University, Rajkot, IndiaFaculty of Pharmacy, Dharmsinh Desai University, Nadiad, IndiaRamanbhai Patel College of Pharmacy, Charotar University of Science and Technology, CHARUSAT- Campus, Changa, Anand, India.Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, CHARUSAT- Campus, Changa, Anand, India.Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, CHARUSAT- Campus, Changa, Anand, India.Quinolines are a prominent heterocyclic motif and crucial building blocks in creating physiologically active compounds. Due to the fast development of novel medicines with a quinoline nucleus, numerous research papers have been published in a short amount of time. Therefore, to comprehend the present state of the quinoline nucleus in medicinal chemistry science, it is necessary to combine new information with older data. So far, several traditional synthesis techniques have been reported in the literature to synthesize this scaffold. Pfitzinger, Gould–Jacob, Friedlander, Skraup, Doebner–von Miller, and Conrad–Limpach are examples of old synthetic methods. However, they need expensive and demanding conditions, such as high temperature, the use of non-biodegradable chemical compounds degrade the ecosystem, create irritation or harm as pollutants, and represent a threat to the environment. However, traditional synthesis processes need a difficult and time-consuming apparatus set-up, resulting in high costs and pollutants. As a result, scientists are presently developing new and innovative techniques to decrease the use of chemicals, solvents, and catalysts, which are detrimental to both humans and the environment. Therefore, we have attempted to shed light in this current review on various reactions to produce quinolines and their derivatives using various green synthetic methods.https://www.tandfonline.com/doi/10.1080/17518253.2022.2064194Quinolinegreen chemistrymicrowave synthesissolvent-free approachmulticomponent reaction |
spellingShingle | Ashish Patel Stuti Patel Meshwa Mehta Yug Patel Rushi Patel Drashti Shah Darshini Patel Umang Shah Mehul Patel Swayamprakash Patel Nilay Solanki Tushar Bambharoliya Sandip Patel Afzal Nagani Harnisha Patel Jitendra Vaghasiya Hirak Shah Bijal Prajapati Mrudangsinh Rathod Bhargav Bhimani Riddhisiddhi Patel Vashisth Bhavsar Brijesh Rakholiya Maitri Patel Prexa Patel A review on synthetic investigation for quinoline- recent green approaches Green Chemistry Letters and Reviews Quinoline green chemistry microwave synthesis solvent-free approach multicomponent reaction |
title | A review on synthetic investigation for quinoline- recent green approaches |
title_full | A review on synthetic investigation for quinoline- recent green approaches |
title_fullStr | A review on synthetic investigation for quinoline- recent green approaches |
title_full_unstemmed | A review on synthetic investigation for quinoline- recent green approaches |
title_short | A review on synthetic investigation for quinoline- recent green approaches |
title_sort | review on synthetic investigation for quinoline recent green approaches |
topic | Quinoline green chemistry microwave synthesis solvent-free approach multicomponent reaction |
url | https://www.tandfonline.com/doi/10.1080/17518253.2022.2064194 |
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