Cachexia index and its relationship with resection operability in patients with gastric adenocarcinoma
Introduction: Gastric cancer is one of the relatively common malignancies all over the world, and is one of major problems of health care system. Nowadays, importance of cachexia is demonstrated in prognosis of various malignancies. The aim of the present study was to evaluate frequency of cachexia...
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| Format: | Article |
| Language: | English |
| Published: |
Tabriz University of Medical Sciences
2018-06-01
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| Series: | Journal of Analytical Research in Clinical Medicine |
| Subjects: | |
| Online Access: | http://journals.tbzmed.ac.ir/JARCM/Manuscript/JARCM-6-93.pdf |
| _version_ | 1818652595041861632 |
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| author | Alireza Barband Farzad Kakaei Reza Javadrashid Mehrangiz Ebrahimi-Mameghani Mohammadreza Mafi |
| author_facet | Alireza Barband Farzad Kakaei Reza Javadrashid Mehrangiz Ebrahimi-Mameghani Mohammadreza Mafi |
| author_sort | Alireza Barband |
| collection | DOAJ |
| description | Introduction: Gastric cancer is one of the relatively common
malignancies all over the world, and is one of major problems of health care
system. Nowadays, importance of cachexia is demonstrated in prognosis of
various malignancies. The aim of the present study was to evaluate frequency of
cachexia index and its relationship with resection operability in patients with
gastric adenocarcinoma.
Methods: In a
descriptive-analytical study, 36 patients with gastric adenocarcinoma who
referred to Imam Reza and Sina educational medical centers of Tabriz University
of Medical Sciences, Tabriz, Iran, for surgery procedures, were included and
evaluated in the study. Skeletal muscle index (SMI) was calculated using
computed tomography (CT)-scan before performing surgery, patients’ cachexia
index was calculated by the following formula:
.
Cachexia syndrome, patients’ weight loss, resection operability, and cachexia
index were evaluated in patients.
Results: Among
36 patients whom were studied, 25 patients (69.4%) were men, and 11 patients
(30.6%) were women. Cachexia was seen in 5 patients (13.9%). In terms of
gastrostomy operability, 26 patients (72.2%) were operable, and 10 patients
(27.8%) were non-operable. Gastrostomy operability in patients with cachexia
were significantly less than patients without cachexia syndrome (P = 0.001). No
significant differences were seen in cachexia index of operable and
non-operable patients (P = 0.105).
Conclusion:
Based on the findings of the present study,
gastrostomy operability in patients with cachexia was significantly less than
patients without cachexia syndrome; but operable and non-operable patients do
not have significant differences in cachexia in comparison to each other. |
| first_indexed | 2024-12-17T02:24:30Z |
| format | Article |
| id | doaj.art-e5de1d0a4b30436ea3c056be0f1bb9ee |
| institution | Directory Open Access Journal |
| issn | 2345-4970 |
| language | English |
| last_indexed | 2024-12-17T02:24:30Z |
| publishDate | 2018-06-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Journal of Analytical Research in Clinical Medicine |
| spelling | doaj.art-e5de1d0a4b30436ea3c056be0f1bb9ee2022-12-21T22:07:10ZengTabriz University of Medical SciencesJournal of Analytical Research in Clinical Medicine2345-49702018-06-0162939710.15171/jarcm.2018.014JARCM_19782_20170927121650Cachexia index and its relationship with resection operability in patients with gastric adenocarcinomaAlireza Barband0Farzad Kakaei1Reza Javadrashid2Mehrangiz Ebrahimi-Mameghani3Mohammadreza Mafi4Department of Surgery, School of Medicine, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Surgery, School of Medicine, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Radiology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Community Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Surgery, School of Medicine, Tabriz University of Medical Sciences, Tabriz, IranIntroduction: Gastric cancer is one of the relatively common malignancies all over the world, and is one of major problems of health care system. Nowadays, importance of cachexia is demonstrated in prognosis of various malignancies. The aim of the present study was to evaluate frequency of cachexia index and its relationship with resection operability in patients with gastric adenocarcinoma. Methods: In a descriptive-analytical study, 36 patients with gastric adenocarcinoma who referred to Imam Reza and Sina educational medical centers of Tabriz University of Medical Sciences, Tabriz, Iran, for surgery procedures, were included and evaluated in the study. Skeletal muscle index (SMI) was calculated using computed tomography (CT)-scan before performing surgery, patients’ cachexia index was calculated by the following formula: . Cachexia syndrome, patients’ weight loss, resection operability, and cachexia index were evaluated in patients. Results: Among 36 patients whom were studied, 25 patients (69.4%) were men, and 11 patients (30.6%) were women. Cachexia was seen in 5 patients (13.9%). In terms of gastrostomy operability, 26 patients (72.2%) were operable, and 10 patients (27.8%) were non-operable. Gastrostomy operability in patients with cachexia were significantly less than patients without cachexia syndrome (P = 0.001). No significant differences were seen in cachexia index of operable and non-operable patients (P = 0.105). Conclusion: Based on the findings of the present study, gastrostomy operability in patients with cachexia was significantly less than patients without cachexia syndrome; but operable and non-operable patients do not have significant differences in cachexia in comparison to each other.http://journals.tbzmed.ac.ir/JARCM/Manuscript/JARCM-6-93.pdfStomach NeoplasmsAdenocarcinomaCachexia |
| spellingShingle | Alireza Barband Farzad Kakaei Reza Javadrashid Mehrangiz Ebrahimi-Mameghani Mohammadreza Mafi Cachexia index and its relationship with resection operability in patients with gastric adenocarcinoma Journal of Analytical Research in Clinical Medicine Stomach Neoplasms Adenocarcinoma Cachexia |
| title | Cachexia index and its relationship with
resection operability in
patients with gastric adenocarcinoma |
| title_full | Cachexia index and its relationship with
resection operability in
patients with gastric adenocarcinoma |
| title_fullStr | Cachexia index and its relationship with
resection operability in
patients with gastric adenocarcinoma |
| title_full_unstemmed | Cachexia index and its relationship with
resection operability in
patients with gastric adenocarcinoma |
| title_short | Cachexia index and its relationship with
resection operability in
patients with gastric adenocarcinoma |
| title_sort | cachexia index and its relationship with resection operability in patients with gastric adenocarcinoma |
| topic | Stomach Neoplasms Adenocarcinoma Cachexia |
| url | http://journals.tbzmed.ac.ir/JARCM/Manuscript/JARCM-6-93.pdf |
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