Malnutrition, cachexia and nutritional intervention: when much becomes too much

Disease-associated malnutrition, also defined as cachexia, is a complex syndrome characterised by the progressive deterioration of nutritional status resulting from the combined effects of reduced appetite and food intake, and profound changes in host metabolism. Cachexia has been repeatedly demonst...

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Main Authors: Serena Rianda, Filippo Rossi Fanelli, Alessandro Laviano
Format: Article
Language:English
Published: SEEd 2013-06-01
Series:Clinical Management Issues
Subjects:
Online Access:https://journals.seedmedicalpublishers.com/index.php/cmi/article/view/647
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author Serena Rianda
Filippo Rossi Fanelli
Alessandro Laviano
author_facet Serena Rianda
Filippo Rossi Fanelli
Alessandro Laviano
author_sort Serena Rianda
collection DOAJ
description Disease-associated malnutrition, also defined as cachexia, is a complex syndrome characterised by the progressive deterioration of nutritional status resulting from the combined effects of reduced appetite and food intake, and profound changes in host metabolism. Cachexia has been repeatedly demonstrated to represent a negative prognostic factor for patients suffering from acute and chronic diseases, including cancer. In oncology patients, early diagnosis of cachexia and timely nutritional intervention have been demonstrated not only to prevent further deterioration of nutritional status, but also to increase quality of life and survival when integrated in a multiprofessional and multidisciplinary approach. However, nutritional therapy is associated to the possible development of complications, which may be fatal. Therefore, nutritional therapy in severely malnourished patients should be cautiously prescribed by experts in the field, who should develop a monitoring program to early detect complications and to maximise the clinical efficacy. Here we describe a cancer patient affected by refeeding syndrome, who was fortunately early diagnosed and properly treated.
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spelling doaj.art-e5e3ecd8b3744a38a11aaa691128d6642022-12-21T19:31:49ZengSEEdClinical Management Issues1973-48322283-31372013-06-0172636910.7175/cmi.v7i2.647653Malnutrition, cachexia and nutritional intervention: when much becomes too muchSerena Rianda0Filippo Rossi Fanelli1Alessandro Laviano2Dipartimento di Medicina Clinica, Sapienza Università di RomaDipartimento di Medicina Clinica, Sapienza Università di RomaDipartimento di Medicina Clinica, Sapienza Università di RomaDisease-associated malnutrition, also defined as cachexia, is a complex syndrome characterised by the progressive deterioration of nutritional status resulting from the combined effects of reduced appetite and food intake, and profound changes in host metabolism. Cachexia has been repeatedly demonstrated to represent a negative prognostic factor for patients suffering from acute and chronic diseases, including cancer. In oncology patients, early diagnosis of cachexia and timely nutritional intervention have been demonstrated not only to prevent further deterioration of nutritional status, but also to increase quality of life and survival when integrated in a multiprofessional and multidisciplinary approach. However, nutritional therapy is associated to the possible development of complications, which may be fatal. Therefore, nutritional therapy in severely malnourished patients should be cautiously prescribed by experts in the field, who should develop a monitoring program to early detect complications and to maximise the clinical efficacy. Here we describe a cancer patient affected by refeeding syndrome, who was fortunately early diagnosed and properly treated.https://journals.seedmedicalpublishers.com/index.php/cmi/article/view/647MalnutritionCachexiaEnteral nutritionComplicationsRefeeding syndromeOral nutritional supplementsMonitoring program
spellingShingle Serena Rianda
Filippo Rossi Fanelli
Alessandro Laviano
Malnutrition, cachexia and nutritional intervention: when much becomes too much
Clinical Management Issues
Malnutrition
Cachexia
Enteral nutrition
Complications
Refeeding syndrome
Oral nutritional supplements
Monitoring program
title Malnutrition, cachexia and nutritional intervention: when much becomes too much
title_full Malnutrition, cachexia and nutritional intervention: when much becomes too much
title_fullStr Malnutrition, cachexia and nutritional intervention: when much becomes too much
title_full_unstemmed Malnutrition, cachexia and nutritional intervention: when much becomes too much
title_short Malnutrition, cachexia and nutritional intervention: when much becomes too much
title_sort malnutrition cachexia and nutritional intervention when much becomes too much
topic Malnutrition
Cachexia
Enteral nutrition
Complications
Refeeding syndrome
Oral nutritional supplements
Monitoring program
url https://journals.seedmedicalpublishers.com/index.php/cmi/article/view/647
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