Delay of cell growth and loss of stemness by inhibition of reverse transcription in human mesenchymal stem cells derived from dental tissue

Delay of cell growth and loss of stemness by inhibition of reverse transcription in human mesenchymal stem cells derived from dental tissue

The present study investigated the cellular properties in the dental tissue-derived mesenchymal stem cells (DSCs) exposed to nevirapine (NVP), an inhibitor of reverse transcriptase (RTase). After a prolonged exposure of DSCs for 2 weeks, the population doubling time (PDT) was significantly (P < ....

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Bibliographic Details
Main Authors: Won-Cheol Lee, Dae-Young Kim, Mi-Jeong Kim, Hyeon-Jeong Lee, Dinesh Bharti, Sung-Ho Lee, Young-Hoon Kang, Gyu-Jin Rho, Byeong-Gyun Jeon
Format: Article
Language:English
Published: Taylor & Francis Group 2019-09-01
Series:Animal Cells and Systems
Subjects:
human mscs
reverse transcriptase
nevirapine
cell growth
differentiation
Online Access:http://dx.doi.org/10.1080/19768354.2019.1651767

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