Short‐term semaglutide treatment improves FGF21 responsiveness in primary hepatocytes isolated from high fat diet challenged mice

Short‐term semaglutide treatment improves FGF21 responsiveness in primary hepatocytes isolated from high fat diet challenged mice

Abstract Metabolic functions of GLP‐1 and its analogues have been extensively investigated. In addition to acting as an incretin and reducing body weight, we and others have suggested the existence of GLP‐1/fibroblast growth factor 21 (FGF21) axis in which liver mediates certain functions of GLP‐1 r...

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Bibliographic Details
Main Authors: Jia Nuo Feng, Weijuan Shao, Tianru Jin
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:Physiological Reports
Subjects:
FGF21
FGF21 resistance
FGFR1
KLB
semaglutide
Online Access:https://doi.org/10.14814/phy2.15620

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